844488-28-4Relevant articles and documents
Norpiperidine imidazoazepines as a new class of potent, selective, and nonsedative H1 antihistamines
Janssens, Frans,Leenaerts, Jos,Diels, Gaston,De Boeck, Beno?t,Megens, Anton,Langlois, Xavier,Van Rossem, Koen,Beetens, Johan,Borgers, Marcel
, p. 2154 - 2166 (2005)
Clinical doses of available H1 antihistamines are limited mainly by sedative side effects. However, higher doses are often required to obtain optimal therapeutic activity, especially in dermatology. We report the synthesis of three norpiperidin