845619-09-2

Basic information

• Product Name: L-Threonine, O-(1,1-dimethylethyl)-N-(1-oxo-4-pentenyl)-, cyanomethyl ester
• CAS NO: 845619-09-2
• Molecular Formula: C15H24N2O4
• Molecular Weight: 296.367
• Mol File: 845619-09-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Threonine, O-(1,1-dimethylethyl)-N-(1-oxo-4-pentenyl)-, cyanomethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Threonine, O-(1,1-dimethylethyl)-N-(1-oxo-4-pentenyl)-, cyanomethyl ester(845619-09-2)
• EPA Substance Registry System: L-Threonine, O-(1,1-dimethylethyl)-N-(1-oxo-4-pentenyl)-, cyanomethyl ester(845619-09-2)

Safety Data

• Hazardous Substances Data: 845619-09-2(Hazardous Substances Data)

Upstream product

• 4378-13-6 (O-tert-butyl)-L-threonine 

Downstream Products

• 845619-11-6 N^α-4-pentenoyl-phospho(1-(2-nitrophenyl)ethyl-2-tert-butyl)-L-threonine cyanomethyl ester 

Relevant articles and documents

Caged phosphoproteins

We present the chemical and biological synthesis of caged phosphoproteins using the in vitro nonsense codon suppression methodology. Specifically, phosphoamino acid analogues of serine, threonine, and tyrosine with a single photocleavable o-nitrophenylethyl caging group were synthesized as the amino acyl tRNA adducts for insertion into full-length proteins. For this purpose, a novel phosphitylating agent was developed. The successful incorporation of these bulky and charged amino acids into the α-subunit of the nicotinic acetyl choline receptor (nAChR) and the vasodilator-stimulated phosphoprotein (VASP) using an in vitro translation system is reported. Copyright