845654-95-7

Basic information

• Product Name: 1-[(2R)-4-benzoyl-2-methyl-piperazin-1-yl]-2-bromo-propan-1-one
• Synonyms: 1-[(2R)-4-benzoyl-2-methyl-piperazin-1-yl]-2-bromo-propan-1-one
• CAS NO: 845654-95-7
• Molecular Weight: 339.232
• Mol File: 845654-95-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[(2R)-4-benzoyl-2-methyl-piperazin-1-yl]-2-bromo-propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2R)-4-benzoyl-2-methyl-piperazin-1-yl]-2-bromo-propan-1-one(845654-95-7)
• EPA Substance Registry System: 1-[(2R)-4-benzoyl-2-methyl-piperazin-1-yl]-2-bromo-propan-1-one(845654-95-7)

Safety Data

• Hazardous Substances Data: 845654-95-7(Hazardous Substances Data)

Upstream product

• 7148-74-5 2-Bromopropionyl chloride 
• 357263-39-9 1-benzoyl-3-(R)-methylpiperazine 

Downstream Products

• 1190089-96-3 C₂₃H₂₇N₃O₄ 
• 1190090-08-4 C₂₃H₂₆FN₃O₄ 
• 1190090-02-8 C₂₄H₂₉N₃O₄ 
• 1190090-03-9 C₂₄H₂₉N₃O₅ 
• 1190090-04-0 C₂₄H₂₆N₄O₃ 
• 1190090-05-1 C₂₄H₂₉N₃O₄ 
• 1190090-06-2 C₂₄H₂₉N₃O₅ 
• 1190090-07-3 C₂₅H₃₁N₃O₅ 
• 1190089-98-5 C₂₃H₂₇N₃O₄ 
• 1190089-99-6 C₂₄H₂₉N₃O₄ 
• 1190090-01-7 C₂₄H₂₉N₃O₄ 
• 1190089-97-4 C₂₃H₂₇N₃O₄ 
• 1190090-00-6 C₂₄H₂₉N₃O₄ 
• 1190841-31-6 C₂₄H₂₅N₃O₃ 

Relevant articles and documents

Discovery of a small molecule inhibitor through interference with the gp120-CD4 interaction

A series of piperazine derivatives were designed and synthesised as gp120-CD4 inhibitors. SAR studies led to the discovery of potent inhibitors in a cell based anti viral assay represented by compounds 9 and 28. The rat pharmacokinetic and antiviral profiles of selected compounds are also presented. Crown Copyright