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845771-78-0

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845771-78-0 Usage

Clinical Use

Antineoplastic agent: Treatment of metastatic colorectal cancer

Drug interactions

Potentially hazardous interactions with other drugs None known

Metabolism

No metabolism studies have been conducted with aflibercept since it is a protein. Aflibercept is expected to degrade to small peptides and individual amino acids. Free aflibercept is mainly cleared by binding to endogenous VEGF to form a stable, inactive complex. As with other large proteins, both free and bound aflibercept, are expected to be cleared, more slowly, by other biological mechanisms, such as proteolytic catabolism.

Check Digit Verification of cas no

The CAS Registry Mumber 845771-78-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,7,7 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 845771-78:
(8*8)+(7*4)+(6*5)+(5*7)+(4*7)+(3*1)+(2*7)+(1*8)=210
210 % 10 = 0
So 845771-78-0 is a valid CAS Registry Number.

845771-78-0Upstream product

845771-78-0Downstream Products

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