845771-78-0 Usage
Clinical Use
Antineoplastic agent:
Treatment of metastatic colorectal cancer
Drug interactions
Potentially hazardous interactions with other drugs
None known
Metabolism
No metabolism studies have been conducted with
aflibercept since it is a protein. Aflibercept is expected to
degrade to small peptides and individual amino acids.
Free aflibercept is mainly cleared by binding to
endogenous VEGF to form a stable, inactive complex. As
with other large proteins, both free and bound aflibercept,
are expected to be cleared, more slowly, by other biological
mechanisms, such as proteolytic catabolism.
Check Digit Verification of cas no
The CAS Registry Mumber 845771-78-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,7,7 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 845771-78:
(8*8)+(7*4)+(6*5)+(5*7)+(4*7)+(3*1)+(2*7)+(1*8)=210
210 % 10 = 0
So 845771-78-0 is a valid CAS Registry Number.