84624-28-2 Usage
Description
N'-Fmoc-L-lysine is an N-Fmoc-protected form of L-Lysine, an essential amino acid for humans. It is crucial for the proper functioning of the body and has a recommended daily intake of 5-8 grams. L-Lysine can be found in various food sources, such as eggs and quinoa, and is also mass-produced through microbial fermentation. Additionally, L-Lysine serves as a therapeutic agent for the treatment of recurrent herpes simplex infections.
Uses
Used in Pharmaceutical Industry:
N'-Fmoc-L-lysine is used as an intermediate in the synthesis of pharmaceutical compounds for various applications, including the development of new drugs and the improvement of existing ones. Its N-Fmoc protection allows for selective deprotection and coupling reactions, facilitating the synthesis of complex peptide-based drugs.
Used in Nutritional Supplements:
N'-Fmoc-L-lysine is used as a nutritional supplement to meet the daily recommended intake of L-Lysine, which is essential for maintaining good health. It can be incorporated into dietary supplements and fortified foods to help individuals who may not be getting enough L-Lysine from their diet.
Used in Research and Development:
N'-Fmoc-L-lysine is utilized in research and development for the study of protein synthesis, enzyme activity, and other biological processes. Its N-Fmoc protection allows for controlled and selective reactions, making it a valuable tool in the development of new therapeutic agents and understanding the underlying mechanisms of various diseases.
Used in Cosmetics and Personal Care:
N'-Fmoc-L-lysine is employed in the cosmetics and personal care industry for its potential benefits in skin health and hair growth. Its incorporation into skincare products and hair care formulations may contribute to improved skin elasticity, collagen production, and hair strength.
Used in Food and Beverage Industry:
N'-Fmoc-L-lysine can be used in the food and beverage industry to fortify products with the essential amino acid L-Lysine. This can help improve the nutritional value of foods and beverages, particularly for individuals who may have specific dietary requirements or need additional L-Lysine intake.
Check Digit Verification of cas no
The CAS Registry Mumber 84624-28-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,6,2 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 84624-28:
(7*8)+(6*4)+(5*6)+(4*2)+(3*4)+(2*2)+(1*8)=142
142 % 10 = 2
So 84624-28-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H24N2O4/c22-19(20(24)25)11-5-6-12-23-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13,22H2,(H,23,26)(H,24,25)/t19-/m0/s1
84624-28-2Relevant articles and documents
Method for selective structural modification of L-lysine
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Paragraph 0025; 0053-0057, (2020/07/15)
The invention belongs to the field of chemical synthesis, and particularly relates to a method for selective structural modification of L-lysine. According to a specific technical scheme in the invention, L-lysine is taken as a raw material, silicon dioxide nanoparticles surface-functionalized by beta-cyclodextrin are taken as a catalyst, water is taken as a solvent, and a reaction is performed for 3-5 hours at 25 DEG C in the presence of an amino protective agent to obtain a final product of the reaction; the final reaction product is subjected to standing, and an upper-layer product is takenand subjected to washing, separating and filtering to obtain selectively-modified L-lysine. The used catalyst is odorless and non-toxic; the synthesis method is simple; catalytic performance is excellent; product separation is easy; the catalyst can be repeatedly used; the method effectively solves the problem that a mixture of a common beta-cyclodextrin catalyzed product and cyclodextrin floatson a liquid level and is difficult to separate, simplifies post-treatment steps, reduces the use amount of an organic solvent, and greatly reduces the amount of waste liquid generated in the stage ofpurification.
Decomposition of copper-amino acid complexes by sodium sulfide
Nowshuddin, Shaik,Reddy, A. Ram
, p. 5159 - 5161 (2007/10/03)
Sodium sulfide very efficiently removes copper from protected amino acid-copper complexes. The copper in the amino acid complex was reduced to insoluble cuprous sulfide and the free amino acid was released in pure form. This method is very convenient and rapid, requiring only 5-10 min and 0.55-0.75 equiv of sodium sulfide.
Chemistry in living cells: Detection of active proteasomes by a two-step labeling strategy
Ovaa, Huib,Van Swieten, Paul F.,Kessler, Benedikt M.,Leeuwenburgh, Michiel A.,Fiebiger, Edda,Van den Nieuwendijk, Adrianus M. C. H.,Galardy, Paul J.,Van der Marel, Gijsbert A.,Ploegh, Hidde L.,Overkleeft, Herman S.
, p. 3626 - 3629 (2007/10/03)
In vivo targeting of the proteasome: Probe 1 is a cell-permeable irreversible inhibitor that alkylates the active-site residues of the proteasome in a Michael fashion. After cell lysis, a biotin moiety is introduced by Staudinger ligation to yield construct 2. This strategy allows activity profiling of the catalytic activities of the proteasome in vivo.
