84682-23-5 Usage
Description
2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL METHYL)-1,3-DIOXOLANE-4-METHANOL is an antifungal chiral drug, characterized by its unique molecular structure that includes a 2,4-dichlorophenyl group, an imidazole ring, and a 1,3-dioxolane-4-methanol moiety. 2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL METHYL)-1,3-DIOXOLANE-4-METHANOL exhibits potent antifungal activity, making it a valuable asset in the development of new treatments for fungal infections.
Uses
Used in Pharmaceutical Industry:
2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL METHYL)-1,3-DIOXOLANE-4-METHANOL is used as an antifungal agent for the treatment of various fungal infections. Its chiral nature allows for the development of targeted therapies that can effectively combat fungal pathogens while minimizing side effects and drug resistance.
Used in Research and Development:
In addition to its clinical applications, 2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL METHYL)-1,3-DIOXOLANE-4-METHANOL is also utilized in research settings to study the mechanisms of antifungal action and to develop new strategies for combating drug-resistant fungal strains. Its unique structure provides a valuable tool for understanding the interactions between antifungal agents and their targets, ultimately contributing to the advancement of antifungal drug discovery.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 84682-23-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,6,8 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 84682-23:
(7*8)+(6*4)+(5*6)+(4*8)+(3*2)+(2*2)+(1*3)=155
155 % 10 = 5
So 84682-23-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H14Cl2N2O3/c15-10-1-2-12(13(16)5-10)14(8-18-4-3-17-9-18)20-7-11(6-19)21-14/h1-5,9,11,19H,6-8H2
84682-23-5Relevant articles and documents
Synthesis, antifungal activity and structure-activity relationships of 2-(alkyl or aryl)-2-(alkyl or polyazol-1-ylmethyl)-4-(polyazol-1-ylmethyl)- 1,3-dioxolanes
Baji,Kimny, Tan,Gasquez,Flammang,Compagnon,Delcourt,Mathieu,Viossat,Morgant,Nguyen-Huy
, p. 637 - 650 (2007/10/03)
A series of 2-(alkyl or aryl)-2-(alkyl or polyazol-1-ylmethyl)-4-(polyazol-1-ylmethyl)-1,3-dioxolanes Ia-u was synthesized and tested in vitro against pathogenic fungi in man, animals and plants: Candida albicans, Aspergillus flavus and Fusarium solani. Compounds Iq-t with two polyazol groups have an in vitro activity against these fungi with MIC (minimum inhibitory concentration) value of 5 μg mL-1.