847254-56-2Relevant articles and documents
The scope of the direct proline-catalyzed asymmetric addition of ketones to imines
Notz, Wolfgang,Watanabe, Shin-Ichi,Chowdari, Naidu S.,Zhong, Guofu,Betancort, Juan M.,Tanaka, Fujie,Barbas III, Carlos F.
, p. 1131 - 1140 (2004)
A full account of catalytic direct asymmetric Mannich-type reactions is presented describing the scope of amino acid-catalyzed additions of unmodified ketones to a large variety of imines. These reactions are performed under very mild, operationally simpl