847608-54-2

Basic information

• Product Name: 3-Pyridinecarboxylic acid, 4-[(4-bromo-2-chlorophenyl)amino]-5-chloro-6-[(2-oxopropyl)amino]-, 1,1-dimethylethyl ester
• CAS NO: 847608-54-2
• Molecular Formula: C19H20BrCl2N3O3
• Molecular Weight: 489.196
• Mol File: 847608-54-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxylic acid, 4-[(4-bromo-2-chlorophenyl)amino]-5-chloro-6-[(2-oxopropyl)amino]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxylic acid, 4-[(4-bromo-2-chlorophenyl)amino]-5-chloro-6-[(2-oxopropyl)amino]-, 1,1-dimethylethyl ester(847608-54-2)
• EPA Substance Registry System: 3-Pyridinecarboxylic acid, 4-[(4-bromo-2-chlorophenyl)amino]-5-chloro-6-[(2-oxopropyl)amino]-, 1,1-dimethylethyl ester(847608-54-2)

Safety Data

• Hazardous Substances Data: 847608-54-2(Hazardous Substances Data)

Upstream product

• 114615-82-6 tetrapropylammonium perruthennate 
• 847608-52-0 4-(4-bromo-2-chlorophenylamino)-5-chloro-6-(2-hydroxypropylamino)-nicotinic acid tert-butyl ester 

Relevant articles and documents

Heterocyclic inhibitors of MEK and methods of use thereof

Disclosed are compounds of the Formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8, R9 and R10, W and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.