847659-07-8

Basic information

• Product Name: Uridine, 2'-deoxy-5-(4-formylphenyl)-
• CAS NO: 847659-07-8
• Molecular Formula: C16H16N2O6
• Molecular Weight: 332.313
• Mol File: 847659-07-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Uridine, 2'-deoxy-5-(4-formylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Uridine, 2'-deoxy-5-(4-formylphenyl)-(847659-07-8)
• EPA Substance Registry System: Uridine, 2'-deoxy-5-(4-formylphenyl)-(847659-07-8)

Safety Data

• Hazardous Substances Data: 847659-07-8(Hazardous Substances Data)

Upstream product

• 87199-17-5 4-formylphenylboronic acid, 
• 54-42-2 5-Iodo-2'-deoxyuridine 

Downstream Products

• 847659-10-3 acetic acid 2-acetoxymethyl-5-(5-{4-[1,3-bis-(tert-butyl-dimethyl-silanyloxy)-4,4,5,5-tetramethyl-imidazolidin-2-yl]-phenyl}-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 847659-11-4 5-{4-[1,3-bis-(tert-butyl-dimethyl-silanyloxy)-4,4,5,5-tetramethyl-imidazolidin-2-yl]-phenyl}-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione 
• 847659-09-0 Acetic acid (2R,3S,5R)-2-acetoxymethyl-5-[5-(4-formyl-phenyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl ester 

Relevant articles and documents

Nucleotide insertion and bypass synthesis of pyrene- and BODIPY-modified oligonucleotides by DNA polymerases

The chromophores pyrene and bordipyrromethenylbenzene directly linked to the 5-position of uridine are tolerated and recognized as thymine derivatives by DNA polymerases in primer extension experiments. The Royal Society of Chemistry.

Water-Soluble Pd-Imidate Complexes: Broadly Applicable Catalysts for the Synthesis of Chemically Modified Nucleosides via Pd-Catalyzed Cross-Coupling

(Figure Presented) A broadly applicable catalyst system consisting of water-soluble Pd-imidate complexes has been enployed for the Suzuki-Miyaura cross-coupling of four different nucleosides in water under mild conditions. The efficient nature of the catalyst system also allowed its application in developing a microwave-assisted protocol with the purpose of expediting the catalytic reaction. Preliminary mechanistic studies, assisted by catalyst poison tests and stoichiometric tests performed using an electrospray ionization spectrometer, revealed the possible presence of a homotopic catalyst system.

New, efficient approach for the ligand-free Suzuki-Miyaura reaction of 5-iodo-2′-deoxyuridine in water

A series of 5-aryl-2′-deoxyuridines was prepared, using ligandless Suzuki-Miyaura cross-coupling reactions in neat water, starting from 5-iodo-2′-deoxyuridine as totally deprotected starting material. This ligand-free process gave good to high isolated yi

Efficient synthesis of unprotected C-5-Aryl/Heteroaryl-2'-deoxyuridine via a suzuki-miyaura reaction in aqueous media

Following our previous results on an environmentally benign one-pot Sonogashira-cyclization protocol to obtain substituted furopyrimidine nucleosides under aqueous conditions, we investigate herein the Suzuki-Miyaura cross-coupling reactions of aryl and h