847665-23-0Relevant articles and documents
Design, synthesis, and evaluation of potent and selective benzoyleneurea-based inhibitors of protein geranylgeranyltransferase-I
Carrico, Dora,Blaskovich, Michelle A.,Bucher, Cynthia J.,Sebti, Sa?d M.,Hamilton, Andrew D.
, p. 677 - 688 (2007/10/03)
A series of novel protein geranylgeranyltransferase-I (PGGTase-I) inhibitors based on a benzoyleneurea scaffold has been synthesized. Using a benzoyleneurea scaffold as a mimetic for the central dipeptide (AA), we have developed CAAX peptidomimetic inhibi