847952-27-6

Basic information

• Product Name: (S)-3-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenoxymethyl}-pyrrolidine-1-carboxylic acid benzyl ester
• CAS NO: 847952-27-6
• Molecular Weight: 485.512
• Mol File: 847952-27-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenoxymethyl}-pyrrolidine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenoxymethyl}-pyrrolidine-1-carboxylic acid benzyl ester(847952-27-6)
• EPA Substance Registry System: (S)-3-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenoxymethyl}-pyrrolidine-1-carboxylic acid benzyl ester(847952-27-6)

Safety Data

• Hazardous Substances Data: 847952-27-6(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 369-34-6 3,4-difluoronitrobenzene 
• 124391-76-0 -(+)-methanol 
• 648418-11-5 (S)-3-(4-Benzyloxycarbonylamino-2-fluoro-phenoxymethyl)-pyrrolidine-1-carboxylic acid benzyl ester 

Downstream Products

• 790702-94-2 N-{(S)-3-[3-Fluoro-4-((S)-1-pyrrolidin-3-ylmethoxy)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 

Relevant articles and documents

Structure-activity relationship in the oxazolidinone-quinolone hybrid series: Influence of the central spacer on the antibacterial activity and the mode of action

Oxazolidinone-quinolone hybrids, which combine the pharmacophores of a quinolone and an oxazolidinone, were synthesised and shown to be active against a variety of susceptible and resistant Gram-positive and Gram-negative bacteria. The nature of the space