847995-41-9Relevant articles and documents
Synthesis and evaluation of double-prodrugs against HIV. Conjugation of D4T with 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, emivirine)-type reverse transcriptase inhibitors via the SATE prodrug approach
Petersen, Lene,J?rgensen, Per T.,Nielsen, Claus,Hansen, Thomas H.,Nielsen, John,Pedersen, Erik B.
, p. 1211 - 1220 (2005)
This paper reports the synthesis and the antiviral activities of new double-prodrugs against HIV based on the known mixed SATE (S-acyl-2-thioethyl) prodrug approach. The monophosphate of the nucleoside reverse transcriptase inhibitor (NRTI) d4T was masked