848046-62-8

Basic information

• Product Name: C₃₆H₄₆N₄O₁₀
• Synonyms: C₃₆H₄₆N₄O₁₀
• CAS NO: 848046-62-8
• Molecular Weight: 694.782
• Mol File: 848046-62-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₆H₄₆N₄O₁₀(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₆H₄₆N₄O₁₀(848046-62-8)
• EPA Substance Registry System: C₃₆H₄₆N₄O₁₀(848046-62-8)

Safety Data

• Hazardous Substances Data: 848046-62-8(Hazardous Substances Data)

Upstream product

• 848046-57-1 C₂₇H₃₅NO₆ 
• 147-94-4 arabinosyl cytosine 

Relevant articles and documents

COMPOUNDS

The invention provides a water-soluble prodrug compound comprising a therapeutically effective moiety coupled via a metabolically cleavable bond to a protein binding moiety, wherein said therapeutically effective moiety has an anticancer, antiinflammatory, antiinfective or antipain effect, said protein binding moiety binds non-covalently to blood proteins, and the protein binding of said compound is at least 100 % higher than that of the therapeutically effective moiety itself, with the exclusion of (i) the monoester of gemcitabine with azelaic acid, (ii) the monoester of dideoxycytidine with 1,12-dodecanedicarboxylic acid, (iii) 2-amino-l,9-dihydro-9(2'-(1-(10-acetyl-decanoyloxy)ethoxymethyl))-guanine, (iv) 5'-cytarabine monoester with 1,4-phenylene diacetic acid, (v) the monoester of metronidazole with 1,4-butanedicarboxylic acid, and (vi) the monoester of metronidazole with 1,6-phenylene diacetic acid; and pre-prodrugs metabolizable thereto.