848469-54-5

Basic information

• Product Name: 8-Azabicyclo[3.2.1]octane-2,8-dicarboxylic acid, 3-[4-(2-thienyl)phenyl]-, 2-methyl 8-(2,2,2-trichloroethyl) ester, (1R,2S,3S,5S)-
• CAS NO: 848469-54-5
• Molecular Formula: C22H22Cl3NO4S
• Molecular Weight: 502.846
• Mol File: 848469-54-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-Azabicyclo[3.2.1]octane-2,8-dicarboxylic acid, 3-[4-(2-thienyl)phenyl]-, 2-methyl 8-(2,2,2-trichloroethyl) ester, (1R,2S,3S,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Azabicyclo[3.2.1]octane-2,8-dicarboxylic acid, 3-[4-(2-thienyl)phenyl]-, 2-methyl 8-(2,2,2-trichloroethyl) ester, (1R,2S,3S,5S)-(848469-54-5)
• EPA Substance Registry System: 8-Azabicyclo[3.2.1]octane-2,8-dicarboxylic acid, 3-[4-(2-thienyl)phenyl]-, 2-methyl 8-(2,2,2-trichloroethyl) ester, (1R,2S,3S,5S)-(848469-54-5)

Safety Data

• Hazardous Substances Data: 848469-54-5(Hazardous Substances Data)

Upstream product

• 135416-43-2 (1R,2S,3S,5S)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester 
• 136794-87-1 (1R,2S,3S,5S)-3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester 
• 1003-09-4 2-bromothiophene 
• 661-69-8 hexamethyldistannane 
• 156496-01-4 (1R,2S,3S,5S)-3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2,8-dicarboxylic acid 2-methyl ester 8-(2,2,2-trichloro-ethyl) ester 

Relevant articles and documents

Synthesis and monoamine transporter affinity of new 2β-carbomethoxy- 3β-[4-(substituted thiophenyl)]phenyltropanes: Discovery of a selective SERT antagonist with picomolar potency

Preparation of cocaine analogues has been aimed largely at development of stable compounds with high affinity and selectivity for the dopamine transporter (DAT). We now report the synthesis and monoamine transporter affinity of 10 new 2β-carbomethoxy-3β-[