848649-94-5 Usage
Description
6-BROMO-1,3-DIHYDRO-INDOLE-2-THIONE is a chemical compound with the molecular formula C8H6BrNS. It is a derivative of indole that contains a bromine and a sulfur atom. 6-BROMO-1,3-DIHYDRO-INDOLE-2-THIONE is commonly used in organic synthesis and pharmaceutical research as a building block for creating various bioactive molecules. It has been studied for potential pharmacological properties, such as anti-cancer, anti-inflammatory, and antimicrobial activities. Additionally, 6-Bromo-1,3-dihydro-indole-2-thione has shown potential in the development of new drugs and therapeutic agents.
Uses
Used in Pharmaceutical Research:
6-BROMO-1,3-DIHYDRO-INDOLE-2-THIONE is used as a building block for creating various bioactive molecules for pharmaceutical research. Its unique structure allows for the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
6-BROMO-1,3-DIHYDRO-INDOLE-2-THIONE is used as a key intermediate in organic synthesis, enabling the creation of a wide range of chemical compounds with potential applications in various industries.
Used in Anticancer Applications:
6-BROMO-1,3-DIHYDRO-INDOLE-2-THIONE is studied for its potential anti-cancer properties, making it a candidate for the development of new cancer treatments.
Used in Anti-inflammatory Applications:
6-BROMO-1,3-DIHYDRO-INDOLE-2-THIONE is researched for its potential anti-inflammatory activities, which could lead to the development of new treatments for inflammatory conditions.
Used in Antimicrobial Applications:
6-BROMO-1,3-DIHYDRO-INDOLE-2-THIONE has shown potential in antimicrobial activities, making it a candidate for the development of new antibiotics and antifungal agents.
Check Digit Verification of cas no
The CAS Registry Mumber 848649-94-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,8,6,4 and 9 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 848649-94:
(8*8)+(7*4)+(6*8)+(5*6)+(4*4)+(3*9)+(2*9)+(1*4)=235
235 % 10 = 5
So 848649-94-5 is a valid CAS Registry Number.
848649-94-5Relevant articles and documents
Synthesis of 2-(Arylthio)indolenines via Chemoselective Arylation of Thio-Oxindoles with Arynes
Saputra, Adi,Fan, Rong,Yao, Tuanli,Chen, Jian,Tan, Jiajing
supporting information, p. 2683 - 2688 (2020/05/18)
A chemoselective S-arylation reaction of thio-oxindoles with arynes is presented. The reaction was performed under mild conditions and provided a straightforward synthesis of 2-(arylthio)indolenines in good to excellent yields. Besides, this simple operat
Concise syntheses of the cruciferous phytoalexins brassilexin, sinalexin, wasalexins, and analogues: Expanding the scope of the Vilsmeier formylation
Pedras, M. Soledade C.,Jha, Mukund
, p. 1828 - 1834 (2007/10/03)
(Chemical Equation Presented) Efficient syntheses of the phytoalexins brassilexin, sinalexin, and analogues are demonstrated through the application of the Vilsmeier formylation to indoline-2-thiones followed by a new aqueous ammonia workup procedure. Similarly, a very concise two-pot synthesis of the phytoalexins wasalexins using sequential formylation-amination of indolin-2-ones is described. Remarkably, this novel aqueous ammonia workup allows the sequential one-pot formylation-amination, expanding substantially the scope of the Vilsmeier formylation of both indoline-2-thiones and indolin-2-ones. The examination of the formylation-amination reaction and optimization of conditions, as well as the syntheses and antifungal activities of several brassilexin analogues, are reported.
