849217-58-9

Basic information

• Product Name: 1,1-Cyclopropanedicarboxamide, N-(3-fluoro-4-hydroxyphenyl)-N'-(4-fluorophenyl)-
• Synonyms: N1-(3-fluoro-4-hydroxyphenyl)-N1'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide;cyclopropane-1,1-dicarboxylic acid (3-fluoro-4-hydroxy-phenyl)-amide-(4-fluoro-phenyl)-amide
• CAS NO: 849217-58-9
• Molecular Formula: C17H14F2N2O3
• Molecular Weight: 332.307
• Mol File: 849217-58-9.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 1,1-Cyclopropanedicarboxamide, N-(3-fluoro-4-hydroxyphenyl)-N'-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Cyclopropanedicarboxamide, N-(3-fluoro-4-hydroxyphenyl)-N'-(4-fluorophenyl)-(849217-58-9)
• EPA Substance Registry System: 1,1-Cyclopropanedicarboxamide, N-(3-fluoro-4-hydroxyphenyl)-N'-(4-fluorophenyl)-(849217-58-9)

Safety Data

• Hazardous Substances Data: 849217-58-9(Hazardous Substances Data)

Usage

Chemical structure

A derivative of cyclopropanedicarboxamide with fluoro and hydroxyphenyl groups attached to the nitrogen atoms.

Potential applications

Pharmaceutical and medicinal uses.

Biological activity

The presence of fluoro and hydroxyphenyl groups suggests potential interactions with biological targets such as enzymes or receptors.

Research and development

Further research and development of this compound may lead to the discovery of novel drugs for the treatment of various diseases or conditions.

Class

It belongs to the class of cyclopropanedicarboxamide compounds, which are known for their various biological activities.

Upstream product

• 849217-57-8 N'-(4-(benzyloxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dimethylamide 
• 849217-48-7 ((4-fluorophenyl)carbamoyl)cyclopropanecarboxylic acid 
• 399-96-2 4-amino-2-fluorophenol 
• 598-10-7 cyclopropane-1,1-dicarboxylic acid 
• 40258-99-9 1-(chlorocarbonyl)cyclopropane-1-carboxylic acid 
• 1559-02-0 diethyl cyclopropane-1,1-dicarboxylate 
• 3697-66-3 1,1-cyclopropanedicarboxylic acid monoethyl ester 
• 371-40-4 4-fluoroaniline 
• 369-34-6 3,4-difluoronitrobenzene 
• 76243-24-8 1-(benzyloxy)-2-fluoro-4-nitrobenzene 
• 168268-00-6 4-(benzyloxy)-3-fluoroaniline 
• 1245931-90-1 ethyl 1-(4-fluorophenylcarbamoyl)cyclopropanecarboxylate 
• 6914-71-2 dimethyl 1,1-cyclopropanedicarboxylate 
• 1345847-71-3 methyl 1-((4-fluorophenyl)amidomethyl)cyclopropyl-1-carboxylate 

Downstream Products

• 849217-65-8 cyclopropane-1,1-dicarboxylic acid [4-(7-benzyloxy-6-methoxy-quinazolin-4-yloxy)-3-fluoro-phenyl]-amide-(4-fluoro-phenyl)-amide 
• 849217-51-2 N-[3-fluoro-4-[[7-benzyloxy-6-methoxy-quinolin-4-yl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 849217-64-7 foretinib 
• 1584219-92-0 N-(3-fluoro-4-((2-((4-((methylsulfonyl)methyl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584219-94-2 N-(3-fluoro-4-((2-((2-methyl-5-((methylsulfonyl)methyl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584219-95-3 N-(3-fluoro-4-((2-((1-((methylsulfonyl)methyl)-1H-pyrazol-3-yl)amino)pyrimidin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584219-96-4 N-(3-fluoro-4-((2-(phenylamino)pyrimidin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584219-98-6 N-(3-fluoro-4-((2-((3-nitrophenyl)amino)pyrimidin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584219-99-7 N-(3-fluoro-4-((2-((4-nitrophenyl)amino)pyrimidin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584220-00-7 N-(3-fluoro-4-((2-((3-methoxyphenyl)amino)pyrimidin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584220-01-8 N-(3-fluoro-4-((2-((4-methoxyphenyl)amino)pyrimidin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584220-02-9 N-(3-fluoro-4-((2-((3-(trifluoromethyl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584220-03-0 N-(4-((2-((4-cyano-3-(trifluoromethyl)phenyl)amino)pyrimidin-4-yl)oxy)-3-fluorophenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 1584220-04-1 N-(4-((2-((2-ethoxyethyl)amino)pyrimidin-4-yl)oxy)-3-fluorophenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 

Relevant articles and documents

Targeted protein degradation c-Met degradation agent as well as preparation method and application thereof

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