84928-99-4

Basic information

• Product Name: 2-azido-N,N-bis(2-azidoethyl)ethanamine
• Synonyms: 2-Azido-N,N-bis(2-azidoethyl)ethanamine; ethanamine, 2-azido-N,N-bis(2-azidoethyl)-
• CAS NO: 84928-99-4
• Molecular Formula: C₆H₁₂N₁₀
• Molecular Weight: 224.2265
• Mol File: 84928-99-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-azido-N,N-bis(2-azidoethyl)ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-azido-N,N-bis(2-azidoethyl)ethanamine(84928-99-4)
• EPA Substance Registry System: 2-azido-N,N-bis(2-azidoethyl)ethanamine(84928-99-4)

Safety Data

• Hazardous Substances Data: 84928-99-4(Hazardous Substances Data)

Usage

Chemical compound

2-azido-N,N-bis(2-azidoethyl)ethanamine

Derivative of

ethylenediamine

Common uses

precursor for the synthesis of energetic materials and azido polymers

Versatile compound

used in the synthesis of various polymers, as a monomer for crosslinking and grafting reactions

Contains

azido groups

Known for

high energetic properties

Can be used in

explosive materials

Important to handle with caution due to

potential explosive nature

Safety precautions

must be followed when working with it

Upstream product

• 102-71-6 triethanolamine 
• 817-09-4 tris-(2-chloroethyl)amine hydrochloride 
• 4097-89-6 2,2',2''-triaminotriethylamine 
• 555-77-1 tris-(2-chloro-ethyl)-amine 

Downstream Products

• 1443056-78-7 C₃₆H₃₆N₁₀O₆ 
• 760952-83-8 tris[2-(4-phenyl-1,2,3-triazol-1-yl)ethyl]amine 

Relevant articles and documents

Clickable amino acid derivative tuned self-assembly of antigen and adjuvant for cancer immunotherapy

Amino acid-tuned self-assembly has become an attractive strategy for constructing various functional materials. Here, a series of dibenzocyclooctyne (DIBO) functionalized amphiphilic amino acid derivatives are designed and screened as building blocks of functional supramolecular self-assembly nanoparticles for cancer immunotherapy. One top-performing supramolecular self-assembly material (named DA6C1) is identified through combinatorial screening, and spherical nanoparticles can be easily prepared by this material tuned multicomponent synergistic self-assembly of ovalbumin (OVA) and CpG oligonucleotide. DA6C1 based nanovaccine can significantly enhance the cellular uptake of OVA and CpG into the same bone marrow derived dendritic cells (BMDCs) and greatly improve the activation of DCs. Moreover, after subcutaneous injection, this nanovaccine flows rapidly to the lymph nodes and elicits strong immune responses to achieve effective prophylactic and therapeutic effect. Therefore, our work highlights the great potential of clickable amino acid derivatives as a convenient and powerful tool to construct nanovaccine for effective immunotherapy.

Synthesis of Novel Energetic Compounds. 6

Reported here are the syntheses and physical properties of five novel energetic aliphatic azido compounds.These include azido nitramines, esters, and amines.The compounds have been characterized in terms of freezing point, refractive index, and impact sensitivity.The properties of these azides indicate that these compounds have a wide liquid range and relatively insensitive to impact.

MULTIVALENT SIALIC ACID DERIVATES

Disclosed is tri- or tetravalent sialic acid derivatives comprising a core moiety to which 3 or 4 sialic acid residues are connected via a linker. Such derivatives inhibit the binding of adenovirus to human cells, whereby infections, such as epidemic keratoconjunctivitis, may be treated or prevented by administration of the tri- or tetravalent sialic acid derivatives.

Synthesis of triazole cages containing C3-symmetric α-cyclic tripeptide scaffold

Two water-soluble C3-symmetric 1,2,3-triazole cages containing α-cyclic tripeptide were efficiently synthesized. The key steps include a click reaction to incorporate l-glutamic or l-aspartic acids to a tripodal linker and a unique one-pot cyclotrimerization.