849348-19-2

Basic information

• Product Name: Benzenesulfonamide, 4-amino-N-[1-(cyclohexylmethyl)-2-(1,1-dimethylethyl)-1H-benzimidazol -5-yl]-N-methyl-
• CAS NO: 849348-19-2
• Molecular Formula: C25H34N4O2S
• Molecular Weight: 454.637
• Mol File: 849348-19-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-amino-N-[1-(cyclohexylmethyl)-2-(1,1-dimethylethyl)-1H-benzimidazol -5-yl]-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-amino-N-[1-(cyclohexylmethyl)-2-(1,1-dimethylethyl)-1H-benzimidazol -5-yl]-N-methyl-(849348-19-2)
• EPA Substance Registry System: Benzenesulfonamide, 4-amino-N-[1-(cyclohexylmethyl)-2-(1,1-dimethylethyl)-1H-benzimidazol -5-yl]-N-methyl-(849348-19-2)

Safety Data

• Hazardous Substances Data: 849348-19-2(Hazardous Substances Data)

Upstream product

• 809237-72-7 2-tert-butyl-1-(cyclohexylmethyl)-N-methyl-1H-benzimidazol-5-amine 
• 24939-24-0 4-aminobenzenesulfonyl chloride 

Downstream Products

• 849350-88-5 2-bromo-N-(4-{[[2-tert-butyl-1-(cyclohexylmethyl)-1H-benzimidazol-5-yl](methyl)amino]sulfonyl}phenyl)acetamide 
• 849351-45-7 methyl (4-{[(1-methylpiperidin-2-yl)methyl]amino}-3-nitrophenyl)carbamate 

Relevant articles and documents

5-sulfonamide benzimidazoles: A class of cannabinoid receptors agonists with potent in vivo antinociception activity

The synthesis and biological evaluation of a novel class of cannabinoid receptor agonists based on a 5-sulfonamide benzimidazole scaffold are reported. They showed a high binding affinity to both receptors with great in vivo potency. When given orally to

BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF

Compounds of Formula (I) or pharmaceutically acceptable salts thereof; wherein R1, R2, R3, R4, n and Ar are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.