849353-34-0

Basic information

• Product Name: 5-AMINO-4-BROMOPYRIMIDINE
• Synonyms: 5-AMINO-4-BROMOPYRIMIDINE;4-bromopyrimidin-5-ylamine
• CAS NO: 849353-34-0
• Molecular Formula: C₄H₄BrN₃
• Molecular Weight: 174.01
• Product Categories: Heterocycle-Pyrimidine series
• Mol File: 849353-34-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 282.2 °C at 760 mmHg
• Flash Point: 124.5 °C
• Appearance: /
• Density: 1.844 g/cm³
• Vapor Pressure: 0.00341mmHg at 25°C
• Refractive Index: 1.648
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 5-AMINO-4-BROMOPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-4-BROMOPYRIMIDINE(849353-34-0)
• EPA Substance Registry System: 5-AMINO-4-BROMOPYRIMIDINE(849353-34-0)

Safety Data

• Hazardous Substances Data: 849353-34-0(Hazardous Substances Data)

Usage

Uses

5-Amino-4-bromopyrimidine is a useful research chemical compound.

InChI:InChI=1/C4H4BrN3/c5-4-3(6)1-7-2-8-4/h1-2H,6H2

Upstream product

• 591-55-9 pyrimidin-5-amine 

Downstream Products

• 1562399-34-1 1-(5-aminopyrimidin-4-yl)-6-(5-fluoro-2-methoxyphenyl)-6-methyl-4-trifluoromethylhept-1-yn-4-ol 
• 1562399-35-2 1-(5-aminopyrimidin-4-yl)-6-(4-fluoro-2-methoxyphenyl)-6-methyl-4-trifluoromethylhept-1-yn-4-ol 
• 1562399-37-4 1-(5-aminopyrimidin-4-yl)-6-(2-methanesulfonylphenyl)-6-methyl-4-trifluoromethylhept-1-yn-4-ol 
• 1562399-39-6 1-(5-aminopyrimidin-4-yl)-6-(3-methanesulfonylphenyl)-6-methyl-4-trifluoromethylhept-1-yn-4-ol 
• 3435-23-2 4-phenylpyrimidin-5-amine 

Relevant articles and documents

Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects

Synthesis and structure-activity relationship (SAR) of a series of nonsteroidal glucocorticoid receptor (GR) agonists are described. These compounds contain "diazaindole" moieties and display different transcriptional regulatory profiles in vitro and are

1,1,1-TRIFLUORO-4-PHENYL-4-METHYL-2-(1H-PYRROLO

Compounds of Formula (IA), IB), IC), and (ID) wherein R1, R2, R3, R4, R5, and R6 are as respectively defined herein for Formula (IA), (IB), (IC), and (ID), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.