849470-63-9Relevant articles and documents
Development of a scaleable process for the synthesis of a next-generation statin
Hobson, Lindsay A.,Akiti, Otute,Deshmukh, Subodh S.,Harper, Shannon,Katipally, Kishta,Lai, Chiajen J.,Livingston, Robert C.,Lo, Ehrlic,Miller, Michael M.,Ramakrishnan, Srividya,Shen, Lifen,Spink, Jan,Tummala, Srinivas,Wei, Chenkou,Yamamoto, Kana,Young, John,Parsons Jr., Rodney L.
, p. 441 - 458 (2011/04/22)
This manuscript details the process research and development of a convergent and safe approach to 1 on a multikilo scale. Specific highlights of the process development efforts will be described, including the development of a dehydrogenation method for d
PYRIMIDINE AND PYRIDINE DERIVATIVES USEFUL AS HMG-COA REDUCTASE INHIBITORS AND METHOD OF PREPARATION THEREOF
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Page/Page column 55-56, (2010/02/11)
Compounds are provided having the following structure which are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol