84954-93-8

Basic information

• Product Name: ROSARIN
• Synonyms: ROSARIN;[(E)-3-Phenyl-2-propenyl]6-O-(α-L-arabinofuranosyl)-β-D-glucopyranoside;[(E)-3-Phenyl-2-propenyl]6-O-α-L-arabinofuranosyl-β-D-glucopyranoside;(2E)-3-phenyl-2-propenyl6-O-.alpha.-L-arabinofuranosyl-(9CI);b-D-Glucopyranoside,(2E)-3-phenyl-2-propen-1-yl 6-O-a-L-arabinofuranosyl-;Rosarin, 98%, from Rhodiola rosea L.
• CAS NO: 84954-93-8
• Molecular Formula: C₂₀H₂₈O₁₀
• Molecular Weight: 428.43
• Product Categories: Miscellaneous Natural Products;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 84954-93-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 730.792 °C at 760 mmHg
• Flash Point: 395.769 °C
• Appearance: Brown fine powder with characteristic odor
• Density: 1.483 g/cm³
• Vapor Pressure: 2.03E-22mmHg at 25°C
• Refractive Index: 1.634
• PKA: 12.89±0.70(Predicted)
• CAS DataBase Reference: ROSARIN(CAS DataBase Reference)
• NIST Chemistry Reference: ROSARIN(84954-93-8)
• EPA Substance Registry System: ROSARIN(84954-93-8)

Safety Data

• Hazardous Substances Data: 84954-93-8(Hazardous Substances Data)

Usage

Description

ROSARIN, a compound with potential health benefits, is known for its preventative effects on belomycin-induced pulmonary fibrosis in rats and chronic obstructive pulmonary disease. It is also utilized in High Performance Thin-Layer Chromatography and NMR spectroscopy for its analytical properties.

Uses

Used in Pharmaceutical Applications:
ROSARIN is used as a preventative agent for [application reason], specifically targeting belomycin-induced pulmonary fibrosis in rats and chronic obstructive pulmonary disease. Its protective effects make it a valuable candidate for further research and potential therapeutic development.
Used in Analytical Chemistry:
In the field of analytical chemistry, ROSARIN is used as a reagent in High Performance Thin-Layer Chromatography (HPTLC) and Nuclear Magnetic Resonance (NMR) spectroscopy. Its properties allow for accurate and efficient analysis in these techniques, contributing to the advancement of chemical research and understanding.

InChI:InChI=1/C20H28O10/c21-9-12-14(22)17(25)20(29-12)28-10-13-15(23)16(24)18(26)19(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19+,20+/m0/s1

Upstream product

• 335591-65-6 2,3,5-tri-O-acetyl-α-L-arabinofuranosyl trichloroacetimidate 
• 913061-09-3 phenyl 2,3,5-tri-O-acetyl-1-thio-α-L-arabinofuranoside 

Downstream Products

• 4510-34-3 (Z)-cinnamyl alcohol 
• 21040-45-9 Cinnamyl acetate 
• 2280-44-6 D-Glucose 
• 87-72-9 L-(+)-arabinose 
• 34047-83-1 (2R,3S,4S,5R,6R)-2-Hydroxymethyl-6-((Z)-3-phenyl-allyloxy)-tetrahydro-pyran-3,4,5-triol 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 

Relevant articles and documents

Synthetic method of rhodiola rosea active ingredient rosavin or rosarin

The present invention provides a synthetic method of rhodiola rosea active ingredient rosavin or rosarin. A convergent synthetic strategy is adopted, rosin is used as a starting material and modifiedinto sugar acceptors through protection and deprotection strategies, then sugar acceptors and sugar donors formed by arabinopyranose and arabinyl furanose in presence of an accelerator quickly and efficiently conduct synthesis of rosavin and rosarin. The related synthetic method is cheap and easy-to-obtain in raw materials and mild in reaction conditions, the obtained product is high in purity, and compared with currently reported linear synthesis strategy, the method has very good industrialization prospects.