850143-44-1

Basic information

• Product Name: Benzeneethanimidamide, N-hydroxy-4-(octadecyloxy)-
• CAS NO: 850143-44-1
• Molecular Formula: C26H46N2O2
• Molecular Weight: 418.663
• Mol File: 850143-44-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzeneethanimidamide, N-hydroxy-4-(octadecyloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanimidamide, N-hydroxy-4-(octadecyloxy)-(850143-44-1)
• EPA Substance Registry System: Benzeneethanimidamide, N-hydroxy-4-(octadecyloxy)-(850143-44-1)

Safety Data

• Hazardous Substances Data: 850143-44-1(Hazardous Substances Data)

Upstream product

• 112-89-0 1-Bromooctadecane 
• 14191-95-8 4-cyanomethylphenol 
• 80280-48-4 2-(4-(octadecyloxy)phenyl)acetonitrile 

Relevant articles and documents

Inhibition of secretory phospholipase A2. 2-Synthesis and structure-activity relationship studies of 4,5-dihydro-3-(4-tetradecyloxybenzyl) -1,2,4-4H-oxadiazol-5-one (PMS1062) derivatives specific for group II enzyme

We have recently reported the discovery of a series of specific inhibitors of human group IIA phospholipase A2 (hGIIA PLA2) to display promising in vitro and in vivo properties. Here we describe the influence of different structural modifications on the specificity and potency against hGIIA PLA2 versus porcine group IB PLA2. The SAR results, as well as the log P and pKa values of oxadiazolone determined in this work, provide important information towards the comprehension of the mode of action of this kind of compounds.