850221-88-4Relevant articles and documents
Synthesis and aldose reductase inhibitory activity of botryllazine A derivatives
Saito, Ryota,Ishibashi, Kana,Noumi, Maiko,Uno, Sota,Higashi, Shoko,Goto, Masaru,Kuwahara, Shunsuke,Komatsu, Toshiya
, p. 556 - 565 (2019/07/22)
Aldose reductase (AR) is associated with the onset of diabetic complications. Botryllazine A and its analogues were synthesized and evaluated for human AR inhibitory activity. Analogues possessing aromatic bicyclic systems at the C5 position of the centra