850397-34-1

Basic information

• Product Name: Acetic acid, 2,2'-[(4-acetyl-1,2-phenylene)bis(oxy)]bis-, diethyl ester
• CAS NO: 850397-34-1
• Molecular Formula: C16H20O7
• Molecular Weight: 324.331
• Mol File: 850397-34-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetic acid, 2,2'-[(4-acetyl-1,2-phenylene)bis(oxy)]bis-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, 2,2'-[(4-acetyl-1,2-phenylene)bis(oxy)]bis-, diethyl ester(850397-34-1)
• EPA Substance Registry System: Acetic acid, 2,2'-[(4-acetyl-1,2-phenylene)bis(oxy)]bis-, diethyl ester(850397-34-1)

Safety Data

• Hazardous Substances Data: 850397-34-1(Hazardous Substances Data)

Upstream product

• 52376-09-7 ethyl 2-<2-<(ethoxycarbonyl)methoxy>phenoxy>acetate 
• 108-24-7 acetic anhydride 
• 1197-09-7 1-(3,4-dihydroxyphenyl)ethan-1-one 
• 105-36-2 ethyl bromoacetate 

Relevant articles and documents

Cell Fixation by Light-Triggered Release of Glutaraldehyde

Chemical fixation of living cells for microscopy is commonly achieved by crosslinking of intracellular proteins with dialdehydes prior to examination. We herein report a photocleavable protecting group for glutaraldehyde that results in a light-triggered and membrane-permeable fixative, which is nontoxic prior to photocleavage. Lipophilic ester groups allow for diffusion across the cell membrane and intracellular accumulation after enzymatic hydrolysis. Irradiation with UV light releases glutaraldehyde. The in situ generated fixative crosslinks intracellular proteins and preserves and stabilizes the cell so that it is ready for microscopy. In contrast to conventional glutaraldehyde fixation, tissue autofluorescence does not increase after fixation. Caged glutaraldehyde may in future enable functional experiments on living cells under a light microscope in which events of interest can be stopped in spatially confined volumes at defined time points. Samples with individually stopped events could then later be analyzed in ultrastructural studies.

Guanidino substituted isoindolones as novel glycoprotein IIb-IIIa receptor antagonists

Design and synthesis of a novel potent glycoprotein IIb-IIIa (GP IIb-IIIa) receptor antagonist based on isoindolone skeleton has been described. This scaffold has been derived from earlier reported pseudopeptides. Synthesis by a novel route has been achieved. Few molecules show very potent in vitro activity. Further identification of probable additional hydrogen bond donor site has been described.