850567-97-4 Usage
Description
2-(METHYLSULFINYL)PHENYLBORONIC ACID is an organic compound that features a boron atom bonded to a phenyl ring with a methylsulfinyl group attached to the 2-position. It is a versatile chemical intermediate with unique properties, making it valuable in various chemical and pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
2-(METHYLSULFINYL)PHENYLBORONIC ACID is used as a pharmaceutical intermediate for the synthesis of various drugs. Its boronic acid functionality allows it to participate in cross-coupling reactions, which are essential for the formation of complex organic molecules with potential therapeutic applications.
Used in Chemical Synthesis:
2-(METHYLSULFINYL)PHENYLBORONIC ACID is used as a chemical building block in the synthesis of various organic compounds. Its ability to form stable bonds with other molecules makes it a useful component in the creation of new chemical entities with diverse properties and potential applications.
Used in Fluorescent Detection:
2-(METHYLSULFINYL)PHENYLBORONIC ACID is used as a fluorescent detection agent for saccharides. 2-(METHYLSULFINYL)PHENYLBORONIC ACID's ability to reversibly bind to diol functional groups allows it to selectively interact with sugars, making it a valuable tool for the detection and analysis of carbohydrate-containing compounds.
Used in Proteasome Inhibition:
2-(METHYLSULFINYL)PHENYLBORONIC ACID is used in the development of proteasome inhibitors, such as Bortezomib. The boronic acid group in this compound plays a crucial role in inhibiting the proteasome, a cellular enzyme complex responsible for the degradation of proteins. This inhibition can have therapeutic effects in the treatment of certain cancers and other diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 850567-97-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,5,6 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 850567-97:
(8*8)+(7*5)+(6*0)+(5*5)+(4*6)+(3*7)+(2*9)+(1*7)=194
194 % 10 = 4
So 850567-97-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H9BO3S/c1-12(11)7-5-3-2-4-6(7)8(9)10/h2-5,9-10H,1H3
850567-97-4Relevant articles and documents
Oxygenation of Organoboronic Acids by a Nonheme Iron(II) Complex: Mimicking Boronic Acid Monooxygenase Activity
Chatterjee, Sayanti,Paine, Tapan Kanti
, p. 9727 - 9732 (2015/11/03)
Phenolic compounds are important intermediates in the bacterial biodegradation of aromatic compounds in the soil. An Arthrobacter sp. strain has been shown to exhibit boronic acid monooxygenase activity through the conversion of different substituted phenylboronic acids to the corresponding phenols using dioxygen. While a number of methods have been reported to cleave the C-B bonds of organoboronic acids, there is no report on biomimetic iron complex exhibiting this activity using dioxygen as the oxidant. In that direction, we have investigated the reactivity of a nucleophilic iron-oxygen oxidant, generated upon oxidative decarboxylation of an iron(II)-benzilate complex [(TpPh2)FeII(benzilate)] (TpPh2 = hydrotris(3,5-diphenyl-pyrazol-1-yl)borate), toward organoboronic acids. The oxidant converts different aryl/alkylboronic acids to the corresponding oxygenated products with the incorporation of one oxygen atom from dioxygen. This method represents an efficient protocol for the oxygenation of boronic acids with dioxygen as the terminal oxidant.
