850568-12-6

Basic information

• Product Name: 4-(N-ETHYLAMINOCARBONYL)PHENYLBORONIC ACID
• Synonyms: 4-(N-ETHYLAMINOCARBONYL)BENZENEBORONIC ACID;4-(N-ETHYLAMINOCARBONYL)PHENYLBORONIC ACID;N-ETHYL 4-BORONOBENZAMIDE;4-(EthylcarbaMoyl)benzeneboronic acid, 98%;Boronic acid,B-[4-[(ethylaMino)carbonyl]phenyl]-;Boronicacid, [4-[(ethylamino)carbonyl]phenyl]- (9CI)
• CAS NO: 850568-12-6
• Molecular Formula: C₉H₁₂BNO₃
• Molecular Weight: 193.01
• Product Categories: blocks;BoronicAcids;Boronic acid
• Mol File: 850568-12-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 143-146°C
• Appearance: /
• Density: 1.19 g/cm³
• Refractive Index: 1.545
• Storage Temp.: Keep Cold
• CAS DataBase Reference: 4-(N-ETHYLAMINOCARBONYL)PHENYLBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(N-ETHYLAMINOCARBONYL)PHENYLBORONIC ACID(850568-12-6)
• EPA Substance Registry System: 4-(N-ETHYLAMINOCARBONYL)PHENYLBORONIC ACID(850568-12-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-36/37/39
• Hazardous Substances Data: 850568-12-6(Hazardous Substances Data)

Usage

General Description

4-(N-Ethylaminocarbonyl)phenylboronic Acid is a chemical compound, notable for its properties as a boronic acid. Boronic acids are typically used in chemical research due to their ability to form stable covalent bonds. 4-(N-Ethylaminocarbonyl)phenylboronic Acid, specifically, is a variety of boronic acid often utilized as a reagent in a range of chemical reactions due to its stability and reactivity. It's commonly used in laboratory and research settings, specifically in organic chemistry, for its potential to participate in a variety of interactions. The actual applications can vary depending on the other compounds and specific processes involved.

InChI:InChI=1/C9H12BNO3/c1-2-11-9(12)7-3-5-8(6-4-7)10(13)14/h3-6,13-14H,2H2,1H3,(H,11,12)

Upstream product

• 75-04-7 ethylamine 
• 332154-57-1 (4-(chlorocarbonyl)phenyl)boronic acid 

Downstream Products

• 1245505-19-4 C₂₀H₁₈N₄O₂ 
• 1146156-91-3 4'-[1-(4-trifluoromethylbenzyl)azetidin-3-yloxy]biphenyl-4-carboxylic acid ethylamide 
• 1451163-33-9 4-[5-(4-ethylcarbamoyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Carboxylic acid recognition of an N-ethyl-substituted diamidine having a diphenylnaphthalene unit in competing protic solvents

A new diphenylnaphthalene-based diamidine (1) having an N-ethyl-substituent to improve its solubility has been designed and synthesized for the recognition of dicarboxylic acids. The diamidine 1 forms 1:1 complexes with the α,ω-dicarboxylic acids in the competing protic solvent, MeOH, using the charge-assisted hydrogen bonding (i.e., formation of amidinium-carboxylate), and the formation of the complexes was determined by 1H NMR and DOSY NMR spectroscopies in a high concentration (2.0 mM). However, at a low concentration (25 μM), the turn-on fluorescence detection of the dicarboxylic acids was not successful because the diamidine 1 emits in MeOH before recognizing the carboxylic acids. Interestingly, the diamidine 1 does not emit in 2-propanaol before recognizing the α,ω-dicarboxylic acids, and succeeded in the detection of a dicarboxylic acid (turn-on response) in the protic solvent, 2-propanol. The interesting tight binding of the diamidine 1 with α,ω-dicarboxylic acids was observed in 2-propanol-d8 using 1H NMR and the restriction of the rotation of the phenyl rings of the 1,8- diphenylnaphthalene unit was also observed. These fluorescence and binding characteristics of the N-ethyl-substituted diamidine 1 are applicable for the detection of carboxylic acids in a protic solvent.