85083-70-1

Basic information

• Product Name: 4-Octanone, 3-hydroxy-2,3-dimethyl-
• CAS NO: 85083-70-1
• Molecular Formula: C10H20O2
• Mol File: 85083-70-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Octanone, 3-hydroxy-2,3-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Octanone, 3-hydroxy-2,3-dimethyl-(85083-70-1)
• EPA Substance Registry System: 4-Octanone, 3-hydroxy-2,3-dimethyl-(85083-70-1)

Safety Data

• Hazardous Substances Data: 85083-70-1(Hazardous Substances Data)

Upstream product

• 563-80-4 3-methyl-butan-2-one 
• 109-72-8 n-butyllithium 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Synthesis of α-Hydroxy Ketones by Direct, Low-Temperature, in Situ Nucleophilic Acylation of Aldehydes and Ketones by Acyllithium Reagents

The reaction of n-, sec-, and tert-butyllithium with CO at atmospheric pressure at -110 and -135 deg C in the appropriate solvent system in the presence of ketones and aldehydes generates the acyllithium, RC(O)Li, which reacts with the carbonyl compound to give the α-hydroxy ketone, generally in good yield.Reactions with aldehydes are limited in scope, working well with the t-BuLi-derived acyllithium reagents, but not with n-BuC(O)Li.