85092-85-9

Basic information

• Product Name: 5-CHLORO-3-IODOINDOLE
• Synonyms: 5-CHLORO-3-IODOINDOLE;5-CHLORO-3-IODO-1H-INDOLE
• CAS NO: 85092-85-9
• Molecular Formula: C₈H₅ClIN
• Molecular Weight: 277.49
• Mol File: 85092-85-9.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 375.6 °C at 760 mmHg
• Flash Point: 180.9 °C
• Appearance: /
• Density: 2.041 g/cm³
• Vapor Pressure: 1.66E-05mmHg at 25°C
• Refractive Index: 1.767
• CAS DataBase Reference: 5-CHLORO-3-IODOINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-3-IODOINDOLE(85092-85-9)
• EPA Substance Registry System: 5-CHLORO-3-IODOINDOLE(85092-85-9)

Safety Data

• Hazardous Substances Data: 85092-85-9(Hazardous Substances Data)

Usage

General Description

5-Chloro-3-iodoindole is a chemical compound with the molecular formula C8H5ClIN. It is a heterocyclic compound consisting of a five-membered ring containing three carbon atoms, one chlorine atom, and one iodine atom. 5-CHLORO-3-IODOINDOLE is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and reactivity make it a valuable building block in organic chemistry, allowing for the creation of complex molecules with diverse properties and applications. Additionally, 5-Chloro-3-iodoindole is also being investigated for potential use in the development of new materials and technologies due to its interesting electronic and optical properties.

InChI:InChI=1/C8H5ClIN/c9-5-1-2-8-6(3-5)7(10)4-11-8/h1-4,11H

Upstream product

• 17422-32-1 5-chloro-1H-indole 
• 63069-48-7 p-chloro-o-iodoaniline 
• 180624-15-1 4-chloro-2-trimethylsilanylethynyl-phenylamine 

Downstream Products

• 1048039-49-1 tert-butyl 5-chloro-3-iodo-1H-indole-1-carboxylate 
• 1218790-30-7 tert-butyl 5-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-1H-indole-1-carboxylate 
• 1448959-35-0 5-chloro-3-iodo-1-tosyl-1H-indole 
• 114306-00-2 3-acetoxy-5-chloroindole 
• 6872-04-4 5,5'-dichloroindigo 

Relevant articles and documents

SMAC MIMETICS USED AS IAP INHIBITORS AND USE THEREOF

Disclosed are a class of SMAC mimetics used as IAP inhibitors, and in particular disclosed are compounds as shown in formula (I), isomers thereof, and pharmaceutically acceptable salts thereof. The IAP inhibitors are drugs for treating cancers, in particu

PhI(OAc)2/NaX-mediated halogenation providing access to valuable synthons 3-haloindole derivatives

This paper describes a mild phenyliodine diacetate mediated method for selective chlorination, bromination, and iodination of indole C-H bonds using sodium halide as a source for analogous halogenations. The combination of NaX and phenyliodine diacetate provides an invincible system for halogenation of indoles. This protocol was compatible with a wide array of indole substrates and provides straight forward access to potential halogenated arenes.

Synthesis of furan-fused 1,4-dihydrocarbazoles via an unusual Garratt-Braverman Cyclization of indolyl propargyl ethers and their antifungal activity

The reactivity of indole based bis-propargyl ethers 4a-4g under Garratt-Braverman condition (KOBut in refluxing toluene) has been studied. Interestingly, these propargyl systems with one arm attached with substituted 3-indolyl derivatives leavi