85107-09-1Relevant articles and documents
Microwave promoted reaction of purin-6-yl magnesium halides with aldehydes in dichloromethane at 100u202f°C
Gordon, Malcolm R.,Lindell, Stephen D.
, p. 1945 - 1947 (2018/04/16)
Treatment of a dichloromethane solution of 9-benzyl or 9-phenyl 6-iodopurine with ethereal ethylmagnesium bromide at ambient temperature gives the corresponding purin-6-yl magnesium halides. Addition of an aldehyde followed by heating at 100 °C in a microwave reactor yielded the corresponding carbinols in 52–81% yield.
Purines. V. Reaction of 9-Phenyl-9H-purine-6-carbonitrile with Nucleophilic Reagents
Higashino, Takeo,Yoshida, Shizuo,Hayashi, Eisaku
, p. 4521 - 4525 (2007/10/02)
The reaction of phenyl-9H-purine-6-carbonitrile (1) with nucleophilic reagents occurred by addition of the reagent across the C-N triple bond of the cyano group, and substitution of the cyano group was not observed.Thus the reaction with hydroxylamine, hy