85115-10-2

Basic information

• Product Name: 3-amino-1,2,3,4-tetrahydroquinolin-2-one
• Synonyms: 3-amino-1,2,3,4-tetrahydroquinolin-2-one
• CAS NO: 85115-10-2
• Molecular Weight: 162.191
• Mol File: 85115-10-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-amino-1,2,3,4-tetrahydroquinolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-1,2,3,4-tetrahydroquinolin-2-one(85115-10-2)
• EPA Substance Registry System: 3-amino-1,2,3,4-tetrahydroquinolin-2-one(85115-10-2)

Safety Data

• Hazardous Substances Data: 85115-10-2(Hazardous Substances Data)

Upstream product

• 7670-65-7 3,6-di(2-nitrobenzylidene)piperazine-2,5-dione 
• 194611-73-9 tert-butyl 2-oxo-1,2,3,4-tetrahydroquinolin-3-ylcarbamate 
• 61548-64-9 ethyl 3-acetamido-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate 
• 243844-36-2 tert-butyl (2-(chloromethyl)phenyl)-carbamate 
• 88-72-2 1-methyl-2-nitrobenzene 
• 1575604-48-6 methyl 2-amino-3-(2-nitrophenyl)propanoate hydrochloride 
• 164648-12-8 2-amino-3-(2-nitrophenyl)propionic acid hydrochloride 
• 6960-47-0 ethyl 2-(acetylamino)-2-(ethoxycarbonyl)-3-(2-nitrophenyl)propanoate 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 552-89-6 2-nitro-benzaldehyde 
• 186545-84-6 3-(2-Amino-phenyl)-2-tert-butoxycarbonylamino-propionic acid ethyl ester 
• 135352-46-4 5-(2-nitro-benzylidene)-imidazolidine-2,4-dione 
• 10034-85-2 hydrogen iodide 
• 7621-81-0 4-(2-nitrobenzylidene)-2-phenyl-5(4H)oxazolone 

Downstream Products

• 872322-45-7 tert-butyl {(1R)-1-(2-fluorobenzyl)-3-oxo-3-[(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)amino]propyl}carbamate 
• 97278-66-5 (S)-2-((R)-1-Carboxymethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-ylamino)-4-phenyl-butyric acid; hydrochloride 
• 97293-68-0 (R)-2-((R)-1-Carboxymethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-ylamino)-4-phenyl-butyric acid; hydrochloride 
• 97278-64-3 (S)-2-((R)-1-Ethoxycarbonylmethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-ylamino)-4-phenyl-butyric acid ethyl ester 

Relevant articles and documents

Novel 3,4-Dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a

The preparation of a series of substituted indoles coupled to six- and seven-membered cyclic lactams is described and their role as human glycogen phosphorylase a inhibitors discussed. The SAR of the indole moiety and lactam ring are presented.

USP30 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of USP30, and the treatment of USP30-mediated disorders.

PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES

Compounds represented by Formula (I) or pharmaceutically acceptable salts thereof, are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.