851231-25-9Relevant articles and documents
MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
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Paragraph 00283, (2020/12/11)
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidases SpsB and/or LepB, an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
Organoiridium complex mixture, and its manufacturing method and an organic electroluminescence element (by machine translation)
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Paragraph 0109; 0110, (2017/01/02)
PROBLEM TO BE SOLVED: To provide an iridium complex mixture that is excellent in solubility in solvents, is high in yield, can easily be produced, and is excellent in the durability of an element, when used for an organic electroluminescent element, to provide an organic electroluminescent element using the iridium complex mixture, and to provide a method for producing the same. SOLUTION: The iridium complex mixture having two or more iridium complexes represented by following general formula (1), wherein bidentate ligands represented by B in the formula (1), of at least two iridium complexes among the two or more iridium complexes are bidentate ligands having the same structure. In (A)mIr(B)n(1), A and B are bidentate ligands having different structures, respectively; A has a structure represented by general formula (2), (wherein, R1, R2and R3are each independently, alkyl); m is an integer of 0 to 2; n is an integer of 1 to 3; m+n=3. COPYRIGHT: (C)2012,JPO&INPIT
PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS
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Page/Page column 67, (2008/06/13)
The present invention relates to pyrrole and pyrazole compounds of formula (I) and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression. The compounds act as potentiators on glutamate receptors, in particular AMPA and the GluR family.