851293-09-9

Basic information

• Product Name: dimethyl 2-(4-bromophenyl)cyclopropane-1,1-dicarboxylate
• Synonyms: dimethyl 2-(4-bromophenyl)cyclopropane-1,1-dicarboxylate
• CAS NO: 851293-09-9
• Molecular Weight: 313.148
• Mol File: 851293-09-9.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: dimethyl 2-(4-bromophenyl)cyclopropane-1,1-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-(4-bromophenyl)cyclopropane-1,1-dicarboxylate(851293-09-9)
• EPA Substance Registry System: dimethyl 2-(4-bromophenyl)cyclopropane-1,1-dicarboxylate(851293-09-9)

Safety Data

• Hazardous Substances Data: 851293-09-9(Hazardous Substances Data)

Upstream product

• 52927-45-4 dimethyl 2-(4-bromobenzylidene)malonate 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 6773-29-1 dimethyl diazomalonate 
• 1122-91-4 4-bromo-benzaldehyde 
• 108-59-8 malonic acid dimethyl ester 
• 868-26-8 dimethyl 2-bromomalonate 
• 1379474-24-4 dimethyl 2-((2-methoxyphenyl)-λ³-iodanylidene)malonate 
• 1774-47-6 trimethylsulfoxonium iodide 

Downstream Products

• 1150306-22-1 dimethyl 2-(4-(chloromethyl)-2-(4-bromophenyl)pent-4-enyl)malonate 

Relevant articles and documents

(3+2)-Cycloaddition of Donor-Acceptor Cyclopropanes with Thiocyanate: A Facile and Efficient Synthesis of 2-Amino-4,5-dihydrothiophenes

An easy and efficient route to obtain 2-amino-4,5-dihydrothiophenes is presented. A formal (3+2)-cycloaddition of donor-acceptor cyclopropanes and ammonium thiocyanate catalyzed by Yb(OTf) 3delivers the desired products in good to excellent yields. A broad range of functional groups is tolerated during this process.

An Expeditious Route to trans-Configured Tetrahydrothiophenes Enabled by Fe(OTf)3-Catalyzed [3+2] Cycloaddition of Donor–Acceptor Cyclopropanes with Thionoesters

A synthetic route to trans-configured tetrahydrothiophenes (THTs) through Fe(OTf)3-promoted [3+2] cycloaddition of donor–acceptor cyclopropanes with thionoesters was developed. The cycloaddition proceeded in high yield with high diastereoselectivity, affording transient α-alkoxy THTs. Not only aromatic and aliphatic thionoesters, but also thionolactone were applicable to the present iron catalysis. Further transformation of the S,O-ketal functionality of the product was achieved in a highly trans diastereoselective manner. Moreover, the utility of our methodology was clearly demonstrated by the synthesis of enantioenriched trans-configured THTs.

Cascade One-Pot Synthesis of Indanone-Fused Cyclopentanes from the Reaction of Donor-Acceptor Cyclopropanes and Enynals via a Sequential Hydrolysis/Knoevenagel Condensation/[3+2] Cycloaddition

A cascade reaction of donor-acceptor cyclopropanes with enynals to construct indanone-fused cyclopentanes via a sequential hydrolysis/Knoevenagel condensation/[3+2] cycloaddition is reported. The desired indanone-fused cyclopentanes were obtained in good yields. This method features mild reaction conditions and broad substrate scope, which render it very appealing to chemists for the synthesis of complex molecules containing an indanone-fused cyclopentane moiety. Moreover, the products could be further converted into compounds with different functional groups through the well-known transformations. (Figure presented.).