851348-65-7

Basic information

• Product Name: Acetic acid, [bis[2-(1,1-dimethylethyl)phenoxy]phosphinyl]-, ethyl ester
• CAS NO: 851348-65-7
• Molecular Formula: C24H33O5P
• Molecular Weight: 432.497
• Mol File: 851348-65-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetic acid, [bis[2-(1,1-dimethylethyl)phenoxy]phosphinyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [bis[2-(1,1-dimethylethyl)phenoxy]phosphinyl]-, ethyl ester(851348-65-7)
• EPA Substance Registry System: Acetic acid, [bis[2-(1,1-dimethylethyl)phenoxy]phosphinyl]-, ethyl ester(851348-65-7)

Safety Data

• Hazardous Substances Data: 851348-65-7(Hazardous Substances Data)

Upstream product

• 851348-76-0 di-(2-tert-butylphenyl) ethyl phosphite 
• 105-36-2 ethyl bromoacetate 
• 133000-13-2 phosphorochloridous acid bis-(2-tert-butyl-phenyl) ester 
• 88-18-6 2-tert-Butylphenol 

Downstream Products

• 7367-88-6 ethyl (E)-2-decenate 
• 7367-88-6 (Z)-dec-2-enoic acid ethyl ester 
• 4610-69-9 (Z)-ethyl cinnamate 
• 18521-02-3 (Z)-ethyl 3-cyclohexylacrylate 
• 17343-88-3 (E)-3-cyclohexyl-acrylic acid ethyl ester 
• 4192-77-2 ethyl cinnamate 
• 103-36-6 ethyl 3-phenyl-2-propenoate 

Relevant articles and documents

Exploiting domino enyne metathesis mechanisms for skeletal diversity generation

In the context of diversity-oriented synthesis, the exploration and optimization of the domino metathesis of decorated norbornenes allowed complex polycyclic architectures to be generated in a highly efficient and atom-economical process. The Royal Society of Chemistry.

Phosphonate modification for a highly (Z)-selective synthesis of unsaturated esters by Horner-Wadsworth-Emmons olefination

The Horner-Wadsworth-Emmons (HWE) reaction of various ethyl diarylphosphonoacetates with benzaldehyde, cyclohexane carboxaldehyde and octanal is reported. Selectivities of up to 98% at -78°C are obtained with the three substrates. Among all the phosphonates prepared, the reagent based on 2-tert-butylphenol proved to be especially efficient, with Z/E ratios close to 95:5 at 0°C. It appears thus to be the reagent of choice for the (Z)-selective HWE reaction with both aromatic and aliphatic aldehydes. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.