851755-56-1 Usage
Description
(R)-2-[1-[[[1-[3-[(E)-2-(7-Ch is a complex organic compound with a specific stereochemistry, denoted by its (R) configuration. (R)-2-[1-[[[1-[3-[(E)-2-(7-Ch has a unique structure that includes various functional groups and molecular moieties, which may contribute to its potential applications in different fields.
Uses
Used in Pharmaceutical Industry:
(R)-2-[1-[[[1-[3-[(E)-2-(7-Ch is used as an impurity in the synthesis of Montelukast, a selective leukotriene D4-receptor antagonist. Montelukast is a medication used for treating asthma and allergic rhinitis by blocking the action of leukotrienes, which are inflammatory mediators. The presence of this impurity in Montelukast may affect the drug's efficacy and safety, making it important to monitor and control its levels during the manufacturing process.
Used in Research and Development:
(R)-2-[1-[[[1-[3-[(E)-2-(7-Ch may also be used as a research compound in the development of new drugs or drug candidates. Its unique structure and stereochemistry could provide valuable insights into the design and synthesis of novel therapeutic agents, particularly in the areas of inflammation, asthma, and allergic diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 851755-56-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,7,5 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 851755-56:
(8*8)+(7*5)+(6*1)+(5*7)+(4*5)+(3*5)+(2*5)+(1*6)=191
191 % 10 = 1
So 851755-56-1 is a valid CAS Registry Number.
851755-56-1Relevant articles and documents
Preparation method of montelukast sodium impurity H
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Paragraph 0012, (2021/09/15)
The invention discloses a method for preparing montelukast sodium impurity H. To the invention 2 - (2 - (3) S (- (2 -chloro 7 - quinolinyl) -2 - vinyl) phenyl) -hydroxypropyl) benzoate (compound -3 - A) is under the catalysis of triethylamine. The method
Asymmetric Catalysis with Iron-Salen Complexes
Shaw, Subrata,White, James D.
, p. 2768 - 2780 (2016/08/31)
Iron(III)-salen complexes based on a chiral cis-2,5-diaminobicyclo[2.2.2]octane scaffold are used as catalysts for a variety of stereo selective reactions. High enantio- and diastereoselectivities can be achieved with these catalysts in sulfa-Michael conjugate addition to acyclic α,β-unsaturated ketones, in regioselective δ-addition of thiols to acyclic α,β,γ,δ-unsaturated ketones, and in Conia-ene carbocyclization of alkynyl-substituted β-dicarbonyl compounds. The use of these chiral iron-salen complexes as catalysts provides a new method for conducting these three important reactions under environmentally sustainable conditions.
PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS
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, (2011/04/14)
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