852064-26-7

Basic information

• Product Name: (E)-dimethyl(phenyl)(4-phenylbut-1-en-1-yl)silane
• Synonyms: (E)-dimethyl(phenyl)(4-phenylbut-1-en-1-yl)silane
• CAS NO: 852064-26-7
• Molecular Weight: 266.458
• Mol File: 852064-26-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-dimethyl(phenyl)(4-phenylbut-1-en-1-yl)silane(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-dimethyl(phenyl)(4-phenylbut-1-en-1-yl)silane(852064-26-7)
• EPA Substance Registry System: (E)-dimethyl(phenyl)(4-phenylbut-1-en-1-yl)silane(852064-26-7)

Safety Data

• Hazardous Substances Data: 852064-26-7(Hazardous Substances Data)

Upstream product

• 33598-22-0 1-Phenyl-3-methylprop-2-yne 
• 768-33-2 phenyldimethylsilyl chloride 
• 184370-59-0 (E)-1-iodo-4-phenyl-1-butene 

Downstream Products

• 852064-38-1 (E)-2-methyl-7-phenylhept-4-en-2-one 
• 182692-62-2 (E)-2,2-dimethyl-7-phenyl-4-hepten-3-one 
• 141191-77-7 trans-1-Phenyl-3-nonen-5-one 
• 33046-41-2 (E)-6-phenyl-3-hexen-2-one 
• 917575-20-3 (E)-1-cyclopropyl-5-phenylpent-2-en-1-one 
• 1239987-82-6 (E)‐1‐(4‐methoxyphenyl)‐5‐phenylpent‐2‐en‐1‐one 
• 134273-12-4 (2E)-5-phenyl-2-pentanophenone 
• 93-97-0 benzoic acid anhydride 

Relevant articles and documents

Direct Access to α,β-Unsaturated Ketones via Rh/MgCl2-Mediated Acylation of Vinylsilanes

We report herein the facile and practical construction of α,β-unsaturated ketones via rhodium-catalyzed direct acylation of vinylsilanes with readily available and abundant carboxylic acids. This protocol features access to a diverse array of synthetically useful functionalities with moderate to excellent yields. More importantly, the late-stage functionalization of pharmaceuticals was also realized with synthetically useful yield.

Rhodium-catalyzed acylation of vinylsilanes with acid anhydrides

A catalytic acylation of vinylsilane with acid anhydride is accomplished by the use of [RhCl(CO)2]2, in which the transmetalation between vinylsilane and rhodium(I) carbonyl complex plays a key role. The application of this acylation reaction to (1-acyloxyvinyl)silanes provides synthetic methods for α-acyloxy enones, α-diketones, and their derivatives.