852148-49-3

Basic information

• Product Name: 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-
• Synonyms: (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-2-oxazolidinone;(S)-4-Benzyl-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)oxazolidin-2-one;(4R,5S)-Methyl 5-(4-(benzyloxy)phenyl)-5-((4-fluorophenyl)aMino)-4-((4S)-2-oxo-4-phenyltetrahydrofuran-3-carbonyl)pentanoate;2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-;Ezetimibe intermediate;2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-
• CAS NO: 852148-49-3
• Molecular Formula: C₂₁H₂₂FNO₄
• Molecular Weight: 371.41
• EINECS: 209-631-8
• Product Categories: Ezetimibe intermediates
• Mol File: 852148-49-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 574.5 °C at 760 mmHg
• Flash Point: 301.2 °C
• Appearance: /
• Density: 1.282 g/cm³
• Storage Temp.: 2-8°C
• PKA: 14.17±0.20(Predicted)
• CAS DataBase Reference: 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-(852148-49-3)
• EPA Substance Registry System: 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)-(852148-49-3)

Safety Data

• Hazardous Substances Data: 852148-49-3(Hazardous Substances Data)

Usage

General Description

The chemical 2-Oxazolidinone,3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-(phenylmethyl)-,(4S)- is a complex organic compound with a 4-(phenylmethyl) oxazolidinone backbone. It contains a 5-(4-fluorophenyl) substituent at the 5th position of the oxazolidinone ring, as well as a 5-hydroxy-1-oxopentyl group. The compound is chiral, with the (5S) and (4S) stereoisomers present. This chemical structure suggests potential pharmaceutical activity, as oxazolidinones are a class of compounds known for their antimicrobial and antibacterial properties. The presence of a phenylmethyl substituent may also indicate potential biological activity, given the common occurrence of aromatic compounds in medicinal chemistry. Further research and testing are likely necessary to fully understand the potential uses and effects of this chemical.

Upstream product

• 149437-76-3 5-(4-fluorophenyl)-5-oxopentanoic acid 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 1056188-47-6 C₁₆H₁₉FO₄ 
• 852148-48-2 (4S)-4-benzyl-3-[5-(4-fluorophenyl)-5-oxopentanoyl]-1,3-oxazolidin-2-one 
• 914777-33-6 1,9-bis(4-fluorophenyl)nonane-1,5,9-trione 

Downstream Products

• 913369-87-6 (4S)-3-[(2R,5S)-2-{(S)-anilino[2-(benzyloxy)-4-bromophenyl]methyl}-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-benzyl-1,3-oxazolidin-2-one 
• 852204-25-2 (3R,4S)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-4-(3,3'-dihydroxybiphenyl-4-yl)-1-phenylazetidin-2-one 
• 916169-47-6 C₃₇H₄₁BrFNO₃Si 
• 852204-18-3 (3R,4S)-4-(4-bromo-2-hydroxyphenyl)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-1-phenylazetidin-2-one 
• 852204-16-1 (3R,4S)-4-[2-(allyloxy)-4-bromophenyl]-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-1-phenylazetidin-2-one 
• 852204-20-7 (3R,4S)-4-(4-bromo-2-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-1-phenylazetidin-2-one 
• 914777-37-0 (3R,4S)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-4-[2-{[tert-butyl(dimethyl)silyl]oxy}-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1-phenylazetidin-2-one 
• 915215-36-0 (4S)-3-[(2R,5S)-2-[(S)-[2-(allyloxy)-4-bromophenyl](anilino)methyl]-5-{[tert-butyl(dimethyl)silyl]oxy}-5-(4-fluorophenyl)pentanoyl]-4-benzyl-1,3-oxazolidin-2-one 
• 852204-60-5 (6S)-6-O-[tert-butyl(dimethyl)silyl]-6-C-(4'-{(2S,3R)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-4-oxo-1-phenylazetidin-2-yl}-3'-hydroxybiphenyl-3-yl)-1,2-O-(1-methylethylidene)-α-D-glucofuranose 
• 852204-51-4 (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-(3'-{[tert-butyl(dimethyl)silyl]oxy}-4'-{(2S,3R)-3-[(3S)-3-{[tert-butyl(dimethyl)silyl]oxy}-3-(4-fluorophenyl)propyl]-4-oxo-1-phenylazetidin-2-yl}biphenyl-3-yl)-D-glucitol 

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