852249-82-2

Basic information

• Product Name: Methanone, [(4S)-4,5-dihydro-4-(2-methylpropyl)-2-oxazolyl]phenyl-
• CAS NO: 852249-82-2
• Molecular Formula: C14H17NO2
• Molecular Weight: 231.294
• Mol File: 852249-82-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methanone, [(4S)-4,5-dihydro-4-(2-methylpropyl)-2-oxazolyl]phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [(4S)-4,5-dihydro-4-(2-methylpropyl)-2-oxazolyl]phenyl-(852249-82-2)
• EPA Substance Registry System: Methanone, [(4S)-4,5-dihydro-4-(2-methylpropyl)-2-oxazolyl]phenyl-(852249-82-2)

Safety Data

• Hazardous Substances Data: 852249-82-2(Hazardous Substances Data)

Upstream product

• 611-73-4 Benzoylformic acid 
• 7533-40-6 (S)-2-amino-4-methylpentan-1-ol 
• 852249-79-7 (S)-N-(1-iso-butyl-2-hydroxyethyl)benzoylformamide 

Relevant articles and documents

Synthesis of new chiral hydroxy oxazolines and their use in the catalytic asymmetric phenyl transfer to aldehydes

Starting either from benzoylformic acid or ethyl oxamate and enantiopure β-amino alcohols, several chiral α-hydroxy oxazolines have been prepared by short synthetic routes. Subsequently, they have been employed in the catalytic asymmetric phenyl transfer to various aldehydes, using a mixture of triphenylborane and diethylzinc as the phenyl source. The corresponding secondary alcohols were obtained with good enantioselectivities (up to 81% ee) and up to 92% yield.