852362-24-4 Usage
Description
PYRIMIDIN-4-YLBORONIC ACID is an organic compound that serves as a versatile intermediate in the synthesis of various pharmaceuticals and organic compounds. It possesses a pyrimidine ring and a boronic acid functional group, which allows it to participate in various chemical reactions, making it a valuable building block in organic synthesis.
Uses
Used in Pharmaceutical Industry:
PYRIMIDIN-4-YLBORONIC ACID is used as an intermediate for the preparation of aldosterone synthase inhibiting pyrimidinylnaphthalenes. These compounds are synthesized via Suzuki cross-coupling reactions and have potential applications in the treatment of cardiovascular and metabolic disorders.
Used in Oncology Research:
PYRIMIDIN-4-YLBORONIC ACID is also used in the synthesis of [7-(2,6-dichlorophenyl)-5-methylbenzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine, which is a potent, orally active Src kinase inhibitor with antitumor activity. PYRIMIDIN-4-YLBORONIC ACID has potential applications in the development of targeted cancer therapies, as Src kinase is involved in various cellular processes, including cell proliferation, survival, and migration.
Check Digit Verification of cas no
The CAS Registry Mumber 852362-24-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,2,3,6 and 2 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 852362-24:
(8*8)+(7*5)+(6*2)+(5*3)+(4*6)+(3*2)+(2*2)+(1*4)=164
164 % 10 = 4
So 852362-24-4 is a valid CAS Registry Number.
InChI:InChI=1/C4H5BN2O2/c8-5(9)4-1-2-6-3-7-4/h1-3,8-9H