85248-86-8 Usage
General Description
(±)-N,N-dimethyl-5-oxopyrrolidine-2-carboxamide is a chemical compound with the molecular formula C7H12N2O2. It is a pyrrolidine derivative with a ketone group and a carboxamide functional group. (±)-N,N-dimethyl-5-oxopyrrolidine-2-carboxamide is commonly used as a building block in organic synthesis and pharmaceutical research. It has potential applications in medicinal chemistry due to its structure and properties. The chemical has been studied for its potential biological activities and therapeutic effects, making it of interest to researchers in the pharmaceutical industry. Additionally, it may also have industrial applications in the synthesis of various organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 85248-86-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,2,4 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 85248-86:
(7*8)+(6*5)+(5*2)+(4*4)+(3*8)+(2*8)+(1*6)=158
158 % 10 = 8
So 85248-86-8 is a valid CAS Registry Number.
85248-86-8Relevant articles and documents
Impact of Functional Groups on the Copper-Initiated N-Arylation of 5-Functionalized Pyrrolidin-2-ones and Their Vinylogues
Baudelet, Davy,Da?ch, Adam,Rigo, Beno?t,Lipka, Emmanuelle,Gautret, Philippe,Homerin, Germain,Claverie, Christelle,Rousseau, Jolanta,Abuhaie, Cristina-Maria,Ghinet, Alina
, p. 2226 - 2244 (2016/07/15)
The electronic effects governing the N-arylation of pyrrolidone were investigated. The generalization of our preliminary findings on a copper(I)-catalyzed Csp2-N coupling process was first improved with a wide variety of aryl and heteroaryl halides and methyl pyroglutamate. The optimized protocol was further extended to pyrrolidin-2-ones substituted at the C5-position with an aryl group bearing an electron-donating or electron-withdrawing group as well as to some of their substituted enaminoester vinylogues. The impact of substituents at the N- and C5-position on these coupling processes seemed to be pivotal for determining both the reaction profiles and yields.