853005-07-9

Basic information

• Product Name: 2-(2,2-Difluoroethoxy)ethanol
• Synonyms: 2-(2,2-Difluoroethoxy)ethanol
• CAS NO: 853005-07-9
• Molecular Formula: C₄H₈F₂O₂
• Molecular Weight: 126.1019264
• Mol File: 853005-07-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 159.4±30.0 °C(Predicted)
• Appearance: /
• Density: 1.149±0.06 g/cm3(Predicted)
• PKA: 14.26±0.10(Predicted)
• CAS DataBase Reference: 2-(2,2-Difluoroethoxy)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-Difluoroethoxy)ethanol(853005-07-9)
• EPA Substance Registry System: 2-(2,2-Difluoroethoxy)ethanol(853005-07-9)

Safety Data

• Hazardous Substances Data: 853005-07-9(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Slightly sweet

Uses

Solvent and intermediate in the production of pharmaceuticals, plastics, and agrochemicals; solvent in cleaning agents and coatings

Volatility

Low

Flammability

Not easily flammable

Safety

Relatively safe and stable to handle, but proper precautions should be taken when handling and storing.

Upstream product

• 359-13-7 difluoroethanol 
• 540-51-2 2-bromoethanol 
• 96-49-1 [1,3]-dioxolan-2-one 

Downstream Products

• 1118567-13-7 2-(2,2-difluoroethoxy)ethyl-4-methylbenzenesulfonate 

Relevant articles and documents

1,2-BIS(2,2-DIFLUOROETHOXY)ETHANE AND MANUFACTURING METHOD THEREOF

1,2-Bis(2,2-difluoroethoxy)ethane which can be used as electrolyte solution of a non-aqueous electrolyte secondary battery is provided. Used are 1,2-Bis(2,2-difluoroethoxy)ethane represented by the following formula (1): and a method for manufacturing 1,2-bis(2,2-difluoroethoxy)ethane including the step of reacting 2-(2,2-difluoroethoxy)ethanol represented by the following formula (2) with a compound represented by the general formula (3) in a basic compound or a basic compound-containing solvent: wherein Lg represents an anionic leaving group.

BENZYLBENZENE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.