853271-15-5

Basic information

• Product Name: 2-(2-bromo-5-methoxyphenyl) propan-2-ol
• Synonyms: 2-(2-bromo-5-methoxyphenyl) propan-2-ol
• CAS NO: 853271-15-5
• Molecular Weight: 245.116
• Mol File: 853271-15-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-(2-bromo-5-methoxyphenyl) propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromo-5-methoxyphenyl) propan-2-ol(853271-15-5)
• EPA Substance Registry System: 2-(2-bromo-5-methoxyphenyl) propan-2-ol(853271-15-5)

Safety Data

• Hazardous Substances Data: 853271-15-5(Hazardous Substances Data)

Upstream product

• 1569316-33-1 [1-(2-bromo-5-methoxyphenyl)-1-methylethoxy](trimethyl)silane 
• 917-64-6 methyl magnesium iodide 
• 6342-63-8 1-(2-bromo-5-methoxyphenyl)ethanone 
• 58733-41-8 5-methoxy-2-bromo benzoic acid ethyl ester 
• 35450-36-3 methyl 2-bromo-5-methoxybenzoate 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 171512-97-3 1-bromo-4-methyloxy-2-(prop-1-en-2-yl)benzene 
• 1569316-33-1 [1-(2-bromo-5-methoxyphenyl)-1-methylethoxy](trimethyl)silane 
• 70603-19-9 6-methoxy-2,3-diphenyl-1H-inden-1-one 
• 1240305-17-2 (E)-N-(1-((2-(dimethylamino)ethyl)amino)-2-methyl-1-oxopropan-2-yl)-4-(4-(2-isopropyl-4-methoxy-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)phenyl)-2,2-dimethylbut-3-enamide 
• 34881-45-3 1-bromo-2-isopropyl-4-methoxy-benzene 
• 1359976-62-7 (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-{5-[(4-bromophenyl)methyl]-2-methoxy-4-(propan-2-yl)phenyl}-D-glucitol 
• 1203447-27-1 4-methoxy-2-(prop-1-en-2-yl)benzoic acid 

Relevant articles and documents

Benzoxaborole Catalyst for Site-Selective Modification of Polyols

The site-selective modification of polyols bearing several hydroxyl groups without the use of protecting groups remains a significant challenge in synthetic chemistry. To address this problem, novel benzoxaborole derivatives were designed as efficient catalysts for the highly site-selective and protecting-group-free modification of polyols. To identify the effective substituent groups enhancing the catalytic activity and selectivity, a series of benzoxaborole catalysts 1a–k were synthesized. In-depth analysis for the substituent effect revealed that 1i–k, bearing multiple electron-withdrawing fluoro- and trifluoromethyl groups, exhibited the greatest catalytic activity and selectivity. Moreover, 1i-catalyzed benzoylation, tosylation, benzylation, and glycosylation of various cis-1,2-diol derivatives proceeded with good yield and site-selective manner.

Copper-Catalyzed Amino Lactonization and Amino Oxygenation of Alkenes Using O-Benzoylhydroxylamines

A copper-catalyzed amino lactonization of unsaturated carboxylic acids has been achieved as well as the analogous intermolecular three-component amino oxygenation of olefins. The transformation features mild conditions and a remarkably broad substrate sco

Substitution controlled functionalization of ortho -bromobenzylic alcohols via palladium catalysis: Synthesis of chromenes and indenols

An efficient domino Pd-catalyzed transformation of simple ortho-bromobenzyl tertiary alcohols to chromenes is presented. Their formation is believed to proceed via the formation of a five-membered palladacycle, which, in turn, involves in an intermolecular homocoupling with the second ortho- bromobenzyltertiary alcohol to yield the homo-biaryl bond followed by intramolecular C-O bond formation. Interestingly, when there is an allylic substituent on the benzylic carbon atom, a chemoselective switch was observed, which preferred intramolecular Heck coupling and gave indenols. Further, it has been confirmed that the tertiary alcohol functionality is indispensible to give the coupled products, whereas the use of primary/secondary benzylic alcohols furnished the simple carbonyl products via a possible reductive debromination followed by oxidation due to the availability of β-hydrogen(s).