85329-87-9

Basic information

• Product Name: (8beta,10xi)-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide
• CAS NO: 85329-87-9
• Molecular Formula: C₂₁H₂₆N₄O₂
• Molecular Weight: 366.4567
• Mol File: 85329-87-9.mol
• Article Data: 1

Chemical Properties

• Density: 1.212g/cm³
• Refractive Index: 1.615
• CAS DataBase Reference: (8beta,10xi)-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (8beta,10xi)-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide(85329-87-9)
• EPA Substance Registry System: (8beta,10xi)-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide(85329-87-9)

Safety Data

• Hazardous Substances Data: 85329-87-9(Hazardous Substances Data)

Usage

Description

(8beta,10xi)-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide is an ergoline derivative with a unique chemical structure, featuring an ethylcarbamoyl group at the 10th position and a prop-2-en-1-yl group at the 6th position of the ergoline ring. As a carboxamide, it possesses a carbonyl group connected to an amino group. (8beta,10xi)-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide exhibits a variety of biological activities, particularly in binding to serotonin and dopamine receptors, making it a valuable asset in the medical field and neuroscience research.

Uses

Used in Pharmaceutical Industry:
(8beta,10xi)-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide is used as an active pharmaceutical ingredient for the treatment of migraines. Its ability to interact with serotonin and dopamine receptors helps alleviate the symptoms associated with migraines, providing relief to patients suffering from this condition.
Used in Neuroscience Research:
In the field of neuroscience, (8beta,10xi)-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide serves as a valuable research tool. Its interaction with serotonin and dopamine receptors allows scientists to study the effects of these neurotransmitters on the brain and develop a deeper understanding of their roles in various neurological processes and disorders.
Used in Drug Development:
(8beta,10xi)-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide is also utilized in the development of new drugs targeting the serotonin and dopamine systems. Its structural features and receptor-binding properties make it a promising candidate for the creation of novel therapeutic agents for a range of neurological and psychiatric conditions, such as Parkinson's disease, schizophrenia, and depression.

Upstream product

• 72821-79-5 methyl (6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate 
• 85329-84-6 6-(2-propenyl)-ergoline-8β-carboxamide 
• 109-90-0 ethyl isocyanate 

Relevant articles and documents

Synthesis and nidation inhibitory activity of a new class of ergoline derivatives

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