853297-42-4

Basic information

• Product Name: Acetamide, N-[4-(1-azetidinylmethyl)-3-(trifluoromethyl)phenyl]-2,2,2-trifluoro-
• CAS NO: 853297-42-4
• Molecular Formula: C13H12F6N2O
• Molecular Weight: 326.241
• Mol File: 853297-42-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[4-(1-azetidinylmethyl)-3-(trifluoromethyl)phenyl]-2,2,2-trifluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[4-(1-azetidinylmethyl)-3-(trifluoromethyl)phenyl]-2,2,2-trifluoro-(853297-42-4)
• EPA Substance Registry System: Acetamide, N-[4-(1-azetidinylmethyl)-3-(trifluoromethyl)phenyl]-2,2,2-trifluoro-(853297-42-4)

Safety Data

• Hazardous Substances Data: 853297-42-4(Hazardous Substances Data)

Upstream product

• 65934-74-9 3-(trifluoromethyl)-4-methylaniline 
• 503-29-7 azetidine 
• 630125-84-7 N-(4-bromomethyl-3-trifluoromethylphenyl)-2,2,2-trifluoroacetamide 

Downstream Products

• 853297-41-3 4-(azetidin-1-ylmethyl)-3-trifluoromethyl-aniline 

Relevant articles and documents

Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8

Using Sorafenib as a starting point, a series of potent and selective inhibitors of CDK8 was developed. When cocrystallized with CDK8 and cyclin C, these compounds exhibit a Type-II (DMG-out) binding mode.