853347-82-7

Basic information

• Product Name: (E)-4-chloro-N-(1-phenylethylidene)-2-(trifluoromethyl)aniline
• Synonyms: (E)-4-chloro-N-(1-phenylethylidene)-2-(trifluoromethyl)aniline
• CAS NO: 853347-82-7
• Molecular Weight: 297.707
• Mol File: 853347-82-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-4-chloro-N-(1-phenylethylidene)-2-(trifluoromethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-chloro-N-(1-phenylethylidene)-2-(trifluoromethyl)aniline(853347-82-7)
• EPA Substance Registry System: (E)-4-chloro-N-(1-phenylethylidene)-2-(trifluoromethyl)aniline(853347-82-7)

Safety Data

• Hazardous Substances Data: 853347-82-7(Hazardous Substances Data)

Upstream product

• 74383-34-9 4-chlorobenzen-2-d-amine 
• 106-47-8 4-chloro-aniline 
• 445-03-4 4-chloro-2-(trifluoromethyl)aniline 
• 98-86-2 acetophenone 

Downstream Products

• 1573117-58-4 6-chloro-2-phenyl-4-(piperidin-1-yl)quinoline 

Relevant articles and documents

Visible-light-promoted radical C-H trifluoromethylation of free anilines

The trifluoromethyl-substituted anilines are biologically active compounds and useful building blocks. In this communication, we have developed the first visible-light-induced radical trifluoromethylation of free anilines with the commercially available and easily handled Togni reagent at room temperature. The resulting products were successfully transformed into a variety of valuable fluorine-containing molecules and heterocyclic compounds. This protocol provides an economical and powerful route to trifluoromethylated free anilines.