85335-73-5

Basic information

• Product Name: Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-
• Synonyms: 5',3'-tetraisopropyl disiloxane-ribocytidine(N-acetyl);3',5'-TIPS-N-Ac-Cytidine;N-Acetyl-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine;N-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine;N-(1-((6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide;3,5-TIPS-N-Ac-C
• CAS NO: 85335-73-5
• Molecular Formula: C₂₃H₄₁N₃O₇Si₂
• Molecular Weight: 551.78324
• EINECS: -0
• Mol File: 85335-73-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.24±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 10.22±0.20(Predicted)
• CAS DataBase Reference: Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-(85335-73-5)
• EPA Substance Registry System: Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-(85335-73-5)

Safety Data

• Hazardous Substances Data: 85335-73-5(Hazardous Substances Data)

Usage

General Description

Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]- is a complex chemical compound. As evident from its structured title, it consists of multiple components. It associates Adenosine, a nucleoside that plays crucial roles in biochemical processes such as energy transfer and signal transduction, with an attached N-acetyl group. The 1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl denotes the siloxane backbone in the compound which has been tetra- substituted with isopropyl groups. The chemical is often used in research and laboratory settings but its specific functions and applications can vary greatly depending on the field and nature of the study or experiment.

Upstream product

• 18043-71-5 1,1,3,3-tetraisopropyldisiloxane 

Downstream Products

• 1403568-00-2 C₂₀H₂₆N₇O₈P 
• 1491026-71-1 C₂₄H₃₂N₅O₈P 
• 1491026-66-4 C₃₆H₆₀N₅O₁₀PSi₂ 
• 1605283-89-3 C₃₀H₄₂N₇O₁₀P 
• 1605283-90-6 C₂₆H₃₆N₇O₉P 
• 1605283-86-0 C₂₆H₃₆N₇O₉P 
• 1403574-71-9 C₂₂H₃₀N₇O₈P 
• 1605283-84-8 C₃₁H₄₂N₅O₁₀P 
• 1605283-80-4 C₃₁H₄₄N₅O₉P 
• 1605283-78-0 C₃₁H₄₄N₅O₉P 
• 1403249-81-9 C₂₁H₂₉N₄O₈PS 
• 1403249-80-8 C₂₂H₂₈N₇O₈P 
• 1403250-92-9 C₂₂H₃₂N₅O₈P 
• 1403250-39-4 C₁₉H₂₄ClN₆O₇P 

Relevant articles and documents

NUCLEIC ACID RELATED COMPOUNDS. 42. A GENERAL PROCEDURE FOR THE EFFICIENT DEOXYGENATION OF SECONDARY ALCOHOLS. REGIOSPECIFIC AND STEREOSELECTIVE CONVERSION OF RIBONUCLEOSIDES TO 2 prime -DEOXYNUCLEOSIDES.

Treatment of unhindered secondary alcohols with phenoxythiocarbonyl chloride (phenyl chlorothionocarbonate) in pyridine/dichloromethane, or in acetonitrile with 4-dimethylaminopyridine catalysis for hindered alcohols, gave clean conversion to their O-phenoxythiocarbonyl derivatives. Reductive deoxygenation of these phenyl thionocarbonate esters proceeded smoothly, using tri-n-butyltin hydride and a free radical initiator in warm toluene. Overall conversion yields ranged from 57 to 78% for the naturally occurring nucleosides, nucleoside antibiotics, and methyl beta -D-ribofuranoside.