853793-24-5

Basic information

• Product Name: N,N-dibenzyl-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
• Synonyms: N,N-dibenzyl-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
• CAS NO: 853793-24-5
• Molecular Weight: 561.628
• Mol File: 853793-24-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N-dibenzyl-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dibenzyl-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide(853793-24-5)
• EPA Substance Registry System: N,N-dibenzyl-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide(853793-24-5)

Safety Data

• Hazardous Substances Data: 853793-24-5(Hazardous Substances Data)

Upstream product

• 428486-70-8 N,N-dibenzyl-p-iodobenzenesulfonamide 
• 26974-15-2 5-(4-methylbenzene)-3-(trifluoromethyl)-1H-pyrazole 
• 766-97-2 4-n-methylphenylacetylene 
• 100-39-0 benzyl bromide 
• 169590-42-5 4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide 
• 96107-01-6 (E)-1,1,1,-trifluoro-4-(p-tolyl)but-3-en-2-one 
• 104-87-0 4-methyl-benzaldehyde 
• 103-49-1 dibenzylamine 
• 98-61-3 p-Iodobenzenesulfonyl chloride 
• 106-38-7 para-bromotoluene 
• 1342899-83-5 N,N-dibenzyl-4-[3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide 

Downstream Products

• 169590-42-5 4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide 

Relevant articles and documents

A Direct Approach to Decoration of Bioactive Compounds via C-H Amination Reaction

The development of new methods to achieve the direct synthesis of bioactive organic molecules is always an important topic in organic synthesis. We hereby demonstrate that N-methoxyamide is an excellent amino source in the iridium-catalyzed intermolecular C-H amination reaction. The linkage of two bioactive organic molecules can be well achieved with this new protocol. More than 20 examples of decorated bioactive compounds were reported, which can facilitate the discovery of new bioactive molecules.

Silver-mediated cycloaddition of alkynes with CF3CHN 2: Highly regioselective synthesis of 3-trifluoromethylpyrazoles

Silver screen: The title reaction provides a convenient and efficient method for the construction of 5-substituted 3-trifluoromethylpyrazoles under mild reaction conditions. By using this protocol, the marketed drug Celecoxib (antiarthritic) could be easily synthesized (see scheme; DMF=N,N- dimethylformamide). Copyright