854399-38-5

Basic information

• Product Name: (S)-2-{(S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-[(2-pyridin-4-yl-thiazole-4-carbonyl)-amino]-propionylamino}-3-hydroxy-propionic acid methyl ester
• CAS NO: 854399-38-5
• Molecular Weight: 632.813
• Mol File: 854399-38-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-{(S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-[(2-pyridin-4-yl-thiazole-4-carbonyl)-amino]-propionylamino}-3-hydroxy-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-{(S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-[(2-pyridin-4-yl-thiazole-4-carbonyl)-amino]-propionylamino}-3-hydroxy-propionic acid methyl ester(854399-38-5)
• EPA Substance Registry System: (S)-2-{(S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-[(2-pyridin-4-yl-thiazole-4-carbonyl)-amino]-propionylamino}-3-hydroxy-propionic acid methyl ester(854399-38-5)

Safety Data

• Hazardous Substances Data: 854399-38-5(Hazardous Substances Data)

Upstream product

• 21278-86-4 2-(4-Pyridyl)-1,3-thiazole-4-carboxylic acid 
• 854399-27-2 3-(tert-butyl-diphenyl-silanyloxy)-2-[(2-pyridin-4-yl-thiazole-4-carbonyl)-amino]-propionic acid 
• 2788-84-3 (S)-serine methyl ester 

Relevant articles and documents

Synthesis of dehydroalanine fragments as thiostrepton side chain mimetics

Syntheses of dehydroalanine derivatives via a solid-support route, starting from selenocystein, and via conventional solution phase chemistry are described along with initial biological testing. The target compounds were designed as mimetics of the dehydroalanine side chain of the macrocyclic antibiotic thiostrepton that acts on the bacterial ribosome.