85452-81-9

Basic information

• Product Name: 4-(diisopropylamino)pyridine
• Synonyms: 4-(diisopropylamino)pyridine
• CAS NO: 85452-81-9
• Molecular Weight: 178.277
• Mol File: 85452-81-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(diisopropylamino)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(diisopropylamino)pyridine(85452-81-9)
• EPA Substance Registry System: 4-(diisopropylamino)pyridine(85452-81-9)

Safety Data

• Hazardous Substances Data: 85452-81-9(Hazardous Substances Data)

Upstream product

• 626-55-1 3-Bromopyridine 
• 96-22-0 pentan-3-one 
• 4111-54-0 lithium diisopropyl amide 
• 109-65-9 1-bromo-butane 

Relevant articles and documents

REACTION DE LA BROMO-3 PYRIDINE AVEC LE DIISOPROPYLAMIDURE DE LITHIUM. MECANISMES DE METALLATION ET DE MIGRATION D'HALOGENE. REGIOSELECTIVITE DE L'ADDITION POLAIRE SUR LA PYRIDYNE-3,4

3-bromo pyridine behaviour towards lithium diisopropyl amide (LDA) in THF is studied.A careful study of the experimental conditions point to a metallation reaction in a position 4 and a "halogen dance" mechanism with isomerisation into a 4-bromo pyridine.Conversion into diisopropylamino compounds occurs simultaneously with a 3 oriented elimination-addition (EA) reaction from transient isomeric lithio-derivatives and a competing addition-elimination (AE) mechanism from the in situ formed 4-bromo pyridine.