854647-56-6Relevant articles and documents
Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals
Wu, Fu-Peng,Li, Da,Peng, Jin-Bao,Wu, Xiao-Feng
supporting information, p. 5699 - 5703 (2019/08/01)
In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.
Highly enantioselective direct alkylation of arylacetic acids with chiral lithium amides as traceless auxiliaries
Stivala, Craig E.,Zakarian, Armen
supporting information; experimental part, p. 11936 - 11939 (2011/09/19)
A direct, highly enantioselective alkylation of arylacetic acids via enediolates using a readily available chiral lithium amide as a stereodirecting reagent has been developed. This approach circumvents the traditional attachment and removal of chiral auxiliaries used currently for this type of transformation. The protocol is operationally simple, and the chiral reagent is readily recoverable.
Enantioselective nucleophilic catalysis: The synthesis of aza-β-lactams through [2+2] cycloadditions of ketenes with azo compounds
Berlin, Jacob M.,Fu, Gregory C.
supporting information; experimental part, p. 7048 - 7050 (2009/04/07)
(Chemical Equation Presented) Get ready for take off: A planar-chiral derivative of 4-pyrrolidinopyridine (1) mediates the title transformation (see scheme) in a convergent manner with good enantioselectivity, thus giving the first catalytic asymmetric synthesis of aza-β-lactams.
