85475-56-5Relevant articles and documents
Synthesis and antiinflammatory activity of alkenylphenylpropionic acids
Amano,Yoshikawa,Ogawa,Sano,Ohuchi,Tanami,Ota,Hatayama,Higuchi,Amanuma
, p. 4653 - 4662 (2007/10/02)
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Process for producing α-arylalkanoic acid ester
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, (2008/06/13)
A process for producing an α-arylalkanoic acid ester represented by the general formula STR1 wherein Ar represents an aryl group which may optionally be substituted, and R1 and R2, independently from each other, represent a lower alkyl group, which comprises reacting a Grignard reagent prepared from an aryl halide of the general formula wherein Ar is as defined above and X1 represents a halogen atom, and magnesium, with an α-haloalkanoic acid ester of the general formula STR2 wherein R1 and R2 are as defined above, and X2 represents a halogen atom, said reaction of the Grignard reagent with the α-haloalkanoic acid ester of general formula (III) being carried out in the presence of a nickel compound.
